| Project/Area Number |
22710064
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Ehime University |
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Principal Investigator |
NOMIYAMA Kei 愛媛大学, 沿岸環境科学研究センタ-, 助教 (30512686)
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| Research Collaborator |
TANABE Shinsuke 愛媛大学, 沿岸環境科学研究センター, 教授 (60116952)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 微量化学物質汚染評価 / 生体内動態 / 陸棲哺乳類 / 有機ハロゲン代謝物 / 環境汚染 / PCBs / PBDEs / 水酸化代謝物 / ネコ / ペット動物 / ペットフード / 水酸化PCBs / 分析法 |
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| Research Abstract |
The present study elucidates the accumulation features of PCBs, PBDEs and their hydroxylated metabolites, and specific differences in metabolic capacities of different species by analyzing the blood samples of various terrestrial mammals. As the results, metabolic capacity of PCBs in terrestrial mammals was found to vary widely among species. Lower chlorinated OH-PCB congeners(3-5 Cl) were predominant in cat blood, whereas higher chlorinated OH-PCBs were found in other mammals. The dominant congeners of OH-/MeO-PBDEs were 6OH-/MeO-BDE47 and 2' OH-/MeO-BDE68 in all the terrestrial mammals, which were already reported as natural products in the marine environment. Moreover, higher accumulation of OH-PBDEs and MeO-PBDEs were found in pet cats than pet dogs, suggesting cats may be intake of these compounds from pet food such as fish. Cats exhibited higher accumulation and a specific pattern of OH-PCBs, OH-PBDEs, and MeO-PBDEs, they may be at a high risk from these metabolites.
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