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Investigation on Newly Synthetic Pulmonary Surfactant Incorporated by Fluorinated Amphiphiles

Research Project

Project/Area Number 22710106
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Nanomaterials/Nanobioscience
Research InstitutionNagasaki International University

Principal Investigator

NAKAHARA Hiromichi  長崎国際大学, 薬学部薬学科, 講師 (00513235)

Co-Investigator(Renkei-kenkyūsha) SHIBATA Osamu  長崎国際大学, 薬学部薬学科, 教授 (10117129)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords表面・界面物性 / 複合材料 / 肺サーファクタント / ナノ医薬 / 超薄膜 / 表面張力 / 表面電位 / 蛍光顕微鏡 / ブリュースター角顕微鏡 / 呼吸窮迫症候群 / 未熟児 / DPPC
Research Abstract

The model peptide in our pulmonary surfactant preparations changes its secondary structure from α-helix to β-sheet upon lateral compression. However, in the presence of anionic lipids such as phosphatidylglycerol and palmitic acid, the conversion of the structure is found to be prevented from the spectroscopic aspect.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (186 results)

All 2013 2012 2011 2010 2009 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (155 results) (of which Invited: 2 results) Book (2 results) Remarks (14 results)

  • [Journal Article] Investigation of interfacial behavior of glycyrrhizin with a lipid raft model via a Langmuir monolayer study2013

    • Author(s)
      坂元政一, 中原広道, 宇都拓洋, 正山征洋, 柴田攻
    • Journal Title

      Biochim. Biophys.Acta

      Volume: 1828 Issue: 4 Pages: 1271-1283

    • DOI

      10.1016/j.bbamem.2013.01.006

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Surfacepressure induced structuraltransitions of an amphiphilic peptidein pulmonary surfactant systems by anin situ PM-IRRAS study2013

    • Author(s)
      中原広道,李相男, 柴田攻
    • Journal Title

      Biochim.Biophys. Acta

      Volume: 1828 Issue: 4 Pages: 1205-1213

    • DOI

      10.1016/j.bbamem.2013.01.003

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Examination of fluorination effect onphysical properties of saturatedlong-chain alcohols by DSC andLangmuir monolayer2013

    • Author(s)
      中原広道,中村承平, 岡橋慶紀, 北口大介,川畑 紀健,坂元政一,柴田攻
    • Journal Title

      Colloids Surf.

      Volume: B102 Pages: 472-478

    • DOI

      10.1016/j.colsurfb.2012.08.031

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fluobodies against bioactive natural products and their application in fluorescence-linked immunosorbent assay2012

    • Author(s)
      坂元政一,Pongkitwitoon B.,中原広道, 柴田攻,正山征洋,田中宏幸, 森元聡
    • Journal Title

      Antibodies

      Volume: 1 Pages: 239-258

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A study on novel artificial lung surfactants incorporated with partially fluorinated amphiphiles2012

    • Author(s)
      中原広道
    • Volume
      132
    • Pages
      817-822
    • NAID

      130001888695

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Langmuir Monolayer Miscibility of Perfluorocarboxylic Acids with Biomembrane Constituents at the Air-Water Interface2012

    • Author(s)
      中原広道, 柴田攻
    • Journal Title

      Journal of Oleo Science

      Volume: 61 Issue: 4 Pages: 197-210

    • DOI

      10.5650/jos.61.197

    • NAID

      130004800055

    • ISSN
      1345-8957, 1347-3352
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surfacepotential of methyl isobutyl carbinoladsorption layer at the air/waterinterface2012

    • Author(s)
      Phan C.M., 中原広道, 柴田攻,師井義清 , Le T.N., Ang H.M.
    • Journal Title

      J. Phys. Chem. B

      Volume: 116 Issue: 3 Pages: 980-986

    • DOI

      10.1021/jp210053u

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Study on Novel Artificial Lung Surfactants Incorporated with Partially Fluorinated Amphiphiles2012

    • Author(s)
      Hiromichi Nakahara
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 132 Pages: 817-822

    • NAID

      130001888695

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluobodies against Bioactive Natural Products and their Application in Fluorescence-Linked Immunosorbent Assay2012

    • Author(s)
      Seiichi Sakamoto
    • Journal Title

      Antibodies

      Volume: 1 Issue: 2 Pages: 239-258

    • DOI

      10.3390/antib1020239

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of palmitic acid inpulmonary surfactant systems byLangmuir monolayer study:Lipid-peptide interactions2011

    • Author(s)
      中原広道, 李相男, 正山征洋, 柴田攻
    • Journal Title

      SoftMatter

      Volume: 7 Issue: 24 Pages: 11351-11359

    • DOI

      10.1039/c1sm06345f

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction of a partiallyfluorinated alcohol(F8H11OH)withbiomembrane constituents intwo-component monolayers2011

    • Author(s)
      中原広道, Krafft M.P., 柴田瑩, 柴田攻
    • Journal Title

      Soft Matter

      Volume: 7 Pages: 7325-7333

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Examination of surface adsorption ofcetyltrimethylammonium bromide andsodium dodecyl sulfate2011

    • Author(s)
      中原 広道,柴田攻,師井義清
    • Journal Title

      J. Phys. Chem.B

      Volume: 115 Issue: 29 Pages: 9077-9086

    • DOI

      10.1021/jp202940p

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction of a partially fluorinated alcohol (F8H11OH) with biomembrane constituents in two-component monolayers2011

    • Author(s)
      Hiromichi Nakahara, et al
    • Journal Title

      Soft Matter

      Volume: 7 Pages: 7325-7333

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluorocarbon-hybrid pulmonarysurfactants for replacement therapy -A Langmuir monolayer study2010

    • Author(s)
      中原広道, 李相男, Krafft M.P., 柴田攻
    • Journal Title

      Langmuir

      Volume: 26 Issue: 23 Pages: 18256-18265

    • DOI

      10.1021/la103118d

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fluorocarbon-Hybrid Pulmonary Surfactants for Replacement Therapy-A Langmuir Monolayer Study2010

    • Author(s)
      Hiromichi Nakahara, et al.
    • Journal Title

      Langmuir

      Volume: 26 Pages: 18256-18265

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脂質ラフト構成分子とステアリルグリチルレチン酸の Langmuir 単分子膜手法による混和挙動解析2013

    • Author(s)
      臼井千尋
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] Perfluoroalkyl 基を有した長鎖アルコールの Langmuir 単分子膜挙動2013

    • Author(s)
      上原聖奈
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] ジェミニ型界面活性剤(14-12-14,2Br-)の溶液物性:難溶性物質の可溶化について2013

    • Author(s)
      小島由意
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F8HmOH)と DPPC の Langmuir 単分子膜挙動2013

    • Author(s)
      柴田攻
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 脂質ラフト生体膜モデルにおけるグリチルレチン酸の界面科学的挙動2013

    • Author(s)
      坂元政一
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] PM-IRRAS 法による肺サーファクタントモデルペプチドの構造解析2013

    • Author(s)
      中原広道
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] PM-IRRAS法による肺サーファクタントモデルペプチドの構造解析2013

    • Author(s)
      中原 広道
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脂質ラフト生体膜モデルにおけるグリチルレチン酸の界面科学的挙動2013

    • Author(s)
      坂元 政一
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F8HmOH)とDPPCのLangmuir単分子膜挙動2013

    • Author(s)
      柴田  攻
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ジェミニ型界面活性剤(14-12-14,2Br−)の溶液物性:難溶性物質の可溶化について2013

    • Author(s)
      小島 由意
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Perfluoroalkyl基を有した長鎖アルコールのLangmuir単分子膜挙動2013

    • Author(s)
      上原 聖奈
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脂質ラフト構成分子とステアリルグリチルレチン酸のLangmuir単分子膜手法による混和挙動解析2013

    • Author(s)
      臼井 千尋
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規部分フッ素化アルコール(FnHmOH)に関する各種物性の熱力学的解析2012

    • Author(s)
      上原聖奈
    • Organizer
      第26 日本薬学会九州支部大会
    • Place of Presentation
      熊本
    • Year and Date
      2012-12-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F8HmOH)と DPPC の二成分単分子膜挙動2012

    • Author(s)
      臼井千尋
    • Organizer
      第26 日本薬学会九州支部大会
    • Place of Presentation
      熊本
    • Year and Date
      2012-12-08
    • Related Report
      2012 Final Research Report
  • [Presentation] ジェミニ型界面活性剤ミセルへの n-アルキルベンゼンの可溶化挙動2012

    • Author(s)
      小島由意
    • Organizer
      第26 日本薬学会九州支部大会
    • Place of Presentation
      熊本
    • Year and Date
      2012-12-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 脂質ラフト生体膜モデルにおけるグリチルレチン酸の単分子膜挙動解析2012

    • Author(s)
      坂元政一
    • Organizer
      第26 日本薬学会九州支部大会
    • Place of Presentation
      熊本
    • Year and Date
      2012-12-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 人工調製肺サーファクタントにおけるペプチド二次構造の解析2012

    • Author(s)
      中原広道
    • Organizer
      第26日本薬学会九州支部大会
    • Place of Presentation
      熊本
    • Year and Date
      2012-12-08
    • Related Report
      2012 Final Research Report
  • [Presentation] ジェミニ 型界面活性剤(14-10-14,2Br-)ミセルへの n-アルキルベンゼンの可溶化2012

    • Author(s)
      小島由意
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2012-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 部分フッ素化両親媒性物質(F8HmOH)と DPPC の二成分混和性の解析2012

    • Author(s)
      臼井千尋
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2012-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規部分フッ素化アルコール(FnHmOH)の単分子膜挙2012

    • Author(s)
      上原聖奈
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2012-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 脂質ラフトモデルにおけるグリチルレチン酸の界面科学的挙動の解析~Langmuir 単分子膜2012

    • Author(s)
      坂元政一
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2012-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 肺サーファクタントモデルにおけるペプチドの二次構造解析2012

    • Author(s)
      中原広道
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2012-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] 人工調製型肺サーファクタントに関する界面化学的研究2012

    • Author(s)
      中原広道
    • Organizer
      日本肺サーファクタント・界面医学会第48回学術研究会
    • Place of Presentation
      福岡
    • Year and Date
      2012-10-27
    • Related Report
      2012 Final Research Report
  • [Presentation] Langmuir monolayer behavior of partially fluorinated alcohols(F8HmOH) and dipalmitoylphosphatidylcholine(DPPC)2012

    • Author(s)
      柴田攻
    • Organizer
      第26回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Malmo, Sweden
    • Year and Date
      2012-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Change in secondary structure of model peptide in pulmonary surfactant systems at the air-water interface2012

    • Author(s)
      中原広道
    • Organizer
      第26回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Malmo,Sweden
    • Year and Date
      2012-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Langmuir monolayer properties of a series of partially fluorinated alcohols2012

    • Author(s)
      中原広道
    • Organizer
      第26回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Malmo,Sweden
    • Year and Date
      2012-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Interaction of glycyrrhizin with lipid rafts model by Langmuir monolayer study2012

    • Author(s)
      坂元政一
    • Organizer
      第26回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Malmo,Sweden
    • Year and Date
      2012-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Palmitic acid controls molecular packing at the air-water interface in pulmonary surfactant model systems2012

    • Author(s)
      中原広道
    • Organizer
      第14回国際組織化膜会議
    • Place of Presentation
      Paris, France
    • Year and Date
      2012-07-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Synthesis, characterization,and surface property of partially fluorinated long-chain alcohols(FnHmOH)2012

    • Author(s)
      中原広道
    • Organizer
      第14回国際組織化膜会議
    • Place of Presentation
      Paris, France
    • Year and Date
      2012-07-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Interfacial behavior ofglycyrrhizin interacted with lipidrafts model by Langmuir monolayer study2012

    • Author(s)
      坂元政一
    • Organizer
      第14回国際組織化膜会議
    • Place of Presentation
      Paris, France
    • Year and Date
      2012-07-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Binary miscibility of partially fluorinated long-chain alcohols (F8HnOH) with dipalmitoylphosphatidylcholine(DPPC) at the air-water interface2012

    • Author(s)
      柴田攻
    • Organizer
      第14回国際組織化膜会議
    • Place of Presentation
      Paris, France
    • Year and Date
      2012-07-12
    • Related Report
      2012 Final Research Report
  • [Presentation] Polarization modulation-infrared reflection absorption spectra of pulmonary surfactant model systems at the air-water interface2012

    • Author(s)
      中原広道
    • Organizer
      第14回国際組織化膜会議
    • Place of Presentation
      Paris, France
    • Year and Date
      2012-07-11
    • Related Report
      2012 Final Research Report
  • [Presentation] Transformation of peptide secondary structure in pulmonary surfactant model systems at the air-water interface2012

    • Author(s)
      中原広道
    • Organizer
      コロイド及び界面化学国際会議
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Langmuir monolayer interactions of perfluorooctylated fatty alcohols (F8HnOH) with dipalmitoylphosphatidylcholine (DPPC)2012

    • Author(s)
      柴田 攻
    • Organizer
      コロイド及び界面化学国際会議
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Surface adsorption behaviorof surfactant solutions from the aspects of Gibbs and Langmuir monolayers2012

    • Author(s)
      柴田 攻
    • Organizer
      コロイド及び界面化学国際会議
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-16
    • Related Report
      2012 Final Research Report
  • [Presentation] In situ polarization-modulation infrared reflection-absorption spectroscopy of pulmonary surfactant model peptide in the DPPC/DPPG systems2012

    • Author(s)
      中原広道
    • Organizer
      コロイド及び界面化学国際会議
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Palmitic acid controls monolayer ordering and squeezing out at the air-water interface in the pulmonary surfactant systems2012

    • Author(s)
      中原広道
    • Organizer
      コロイド及び界面化学国際会議
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Interfacial behavior of glycyrrhizin interacted with lipid rafts model by Langmuir monolayer study2012

    • Author(s)
      坂元 政一
    • Organizer
      コロイド及び界面化学国際会議
    • Place of Presentation
      仙台
    • Year and Date
      2012-05-14
    • Related Report
      2012 Final Research Report
  • [Presentation] 肺サーファクタント系におけるモデルペプチドとパルミチン酸の特異的相互作用2012

    • Author(s)
      中原広道
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F4H11OH)と生体膜モデルである DPPC単分子膜との混和挙動2012

    • Author(s)
      柴田 攻
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] Palmitic acid controls monolayer ordering and squeezing out at the air-water interface in the pulmonary surfactant systems2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      International Association of Colloid and Interface Scientists 2012(IACIS2012)
    • Place of Presentation
      Sendai International Center (SENDAI, JAPAN)
    • Related Report
      2012 Annual Research Report
  • [Presentation] In situ polarization-modulation infrared reflection-absorption spectroscopy of pulmonary surfactant model peptide in the DPPC/DPPG systems2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      International Association of Colloid and Interface Scientists 2012(IACIS2012)
    • Place of Presentation
      Sendai International Center (SENDAI, JAPAN)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Surface adsorption behavior of surfactant solutions from the aspects of Gibbs and Langmuir monolayers2012

    • Author(s)
      Osamu Shibata
    • Organizer
      International Association of Colloid and Interface Scientists 2012(IACIS2012)
    • Place of Presentation
      Sendai International Center (SENDAI, JAPAN)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Langmuir monolayer interactions of perfluorooctylated fatty alcohols (F8HnOH) with dipalmitoylphosphatidylcholine (DPPC)2012

    • Author(s)
      Osamu Shibata
    • Organizer
      International Association of Colloid and Interface Scientists 2012(IACIS2012)
    • Place of Presentation
      Sendai International Center (SENDAI, JAPAN)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Transformation of peptide secondary structure in pulmonary surfactant model systems at the air-water interface2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      International Association of Colloid and Interface Scientists 2012(IACIS2012)
    • Place of Presentation
      Sendai International Center (SENDAI, JAPAN)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Behavior of Glycyrrhizin Interacted with Lipid Rafts Model by Langmuir Monolayer Study2012

    • Author(s)
      Seiichi Sakamoto
    • Organizer
      International Association of Colloid and Interface Scientists 2012(IACIS2012)
    • Place of Presentation
      Sendai International Center (SENDAI, JAPAN)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Binary miscibility of partially fluorinated long-chain alcohols (F8HnOH) with dipalmitoylphosphatidylcholine (DPPC) at the air-water interface2012

    • Author(s)
      Osamu Shibata
    • Organizer
      14th INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (ICOMF14-LB14)
    • Place of Presentation
      Paris Descartes University (Paris, France)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Interfacial behavior of glycyrrhizin interacted with lipid rafts model by Langmuir monolayer study2012

    • Author(s)
      Seiichi Sakamoto
    • Organizer
      14th INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (ICOMF14-LB14)
    • Place of Presentation
      Paris Descartes University (Paris, France)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Synthesis, characterization, and surface property of partially fluorinated long-chain alcohols (FnHmOH)2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      14th INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (ICOMF14-LB14)
    • Place of Presentation
      Paris Descartes University (Paris, France)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Palmitic acid controls molecular packing at the air-water interface in pulmonary surfactant model systems2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      14th INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (ICOMF14-LB14)
    • Place of Presentation
      Paris Descartes University (Paris, France)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Polarization modulation-infrared reflection absorption spectra of pulmonary surfactant model systems at the air-water interface,2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      14th INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS (ICOMF14-LB14)
    • Place of Presentation
      Paris Descartes University (Paris, France)
    • Related Report
      2012 Annual Research Report
  • [Presentation] of Glycyrrhizin with Lipid Rafts Model by Langmuir Monolayer Study2012

    • Author(s)
      Seiichi Sakamoto
    • Organizer
      CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      Malmö University (Malmö, Sweden)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Langmuir monolayer properties of a series of partially fluorinated alcohols2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      Malmö University (Malmö, Sweden)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Change in secondary structure of model peptide in pulmonary surfactant systems at the air-water interface2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      Malmö University (Malmö, Sweden)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Langmuir monolayer behavior of partially fluorinated alcohols (F8HmOH) and dipalmitoylphosphatidylcholine (DPPC)2012

    • Author(s)
      Osamu Shibata
    • Organizer
      CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      Malmö University (Malmö, Sweden)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Interfacial phenomena of pulmonary surfactant model systems incorporated with fluorinated amphiphile2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      WORLD CONGRESS ON OLEO SCIENCE & 29TH ISF CONGRESS (WCOS 2012)
    • Place of Presentation
      Arkas Sasebo (Nagasaki, Japan)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Effect of added salt concentrations on surface adsorption of typical surfactants2012

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      WORLD CONGRESS ON OLEO SCIENCE & 29TH ISF CONGRESS (WCOS 2012)
    • Place of Presentation
      Arkas Sasebo (Nagasaki, Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Surface property and miscibility of a partially fluorinated amphiphile (F4H11OH) with dipalmitoylphosphatidylcholine2012

    • Author(s)
      Osamu Shibata
    • Organizer
      WORLD CONGRESS ON OLEO SCIENCE & 29TH ISF CONGRESS (WCOS 2012)
    • Place of Presentation
      Arkas Sasebo (Nagasaki, Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Surface property of a partially fluorinated amphiphile (F8HmOH): Binary miscibility with dipalmitoylphosphatidylcholine2012

    • Author(s)
      Chikayo Hirano
    • Organizer
      WORLD CONGRESS ON OLEO SCIENCE & 29TH ISF CONGRESS (WCOS 2012)
    • Place of Presentation
      Arkas Sasebo (Nagasaki, Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Interaction of Glycyrrhizin with lipid rafts model at the air/water interface2012

    • Author(s)
      Seiichi Sakamoto
    • Organizer
      WORLD CONGRESS ON OLEO SCIENCE & 29TH ISF CONGRESS (WCOS 2012)
    • Place of Presentation
      Arkas Sasebo (Nagasaki, Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 人工調製型肺サーファクタントに関する界面化学的研究2012

    • Author(s)
      中原 広道
    • Organizer
      日本肺サーファクタント・界面医学会第48回学術研究会
    • Place of Presentation
      熊本大学 (熊本)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 肺サーファクタントモデルにおけるペプチドの二次構造解析2012

    • Author(s)
      中原 広道
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大学 (福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脂質ラフトモデルにおけるグリチルレチン酸の界面科学的挙動の解析~Langmuir単分子膜2012

    • Author(s)
      坂元 政一
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大学 (福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規部分フッ素化アルコール(FnHmOH)の単分子膜挙動2012

    • Author(s)
      上原 聖奈
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大学 (福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 部分フッ素化両親媒性物質(F8HmOH)とDPPCの二成分混和性の解析2012

    • Author(s)
      臼井 千尋
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大学 (福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ジェミニ型界面活性剤(14-10-14,2Br−)ミセルへのn-アルキルベンゼンの可溶化2012

    • Author(s)
      小島 由意
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大学 (福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 人工調製肺サーファクタントにおけるペプチド二次構造の解析2012

    • Author(s)
      中原 広道
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学 (熊本)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 脂質ラフト生体膜モデルにおけるグリチルレチン酸の単分子膜挙動解析2012

    • Author(s)
      坂元 政一
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学 (熊本)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ジェミニ型界面活性剤ミセルへのn-アルキルベンゼンの可溶化挙動2012

    • Author(s)
      小島 由意
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学 (熊本)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F8HmOH)とDPPCの二成分単分子膜挙動2012

    • Author(s)
      臼井 千尋
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学 (熊本)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新規部分フッ素化アルコール(FnHmOH)に関する各種物性の熱力学的解析2012

    • Author(s)
      上原 聖奈
    • Organizer
      第29回日本薬学会九州支部大会
    • Place of Presentation
      熊本大学 (熊本)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Surface potential of MIBC at air/water interface : a molecular dynamics study2011

    • Author(s)
      Chi Phan
    • Organizer
      International Symposium on Surface Science (ISSS-6)
    • Place of Presentation
      TOKYO (JAPAN)
    • Year and Date
      2011-12-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肺サーファクタントにおける添加物パルミチン酸の特異的機能2011

    • Author(s)
      中原広道
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Year and Date
      2011-12-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規人工調製肺サーファクタントの研究と高機能性特化への応用展開2011

    • Author(s)
      中原広道
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡
    • Year and Date
      2011-12-10
    • Related Report
      2012 Final Research Report
  • [Presentation] 肺サーファクタントにおける添加物パルミチン酸の特異的機能2011

    • Author(s)
      中原広道
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脂質ラフトモデルにおけるグリチルリチンの界面科学的挙動2011

    • Author(s)
      坂元政一
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規部分フッ素化アルコール(F4H11OH)の単分子膜挙動とDPPCとの混和性の検討2011

    • Author(s)
      平野千佳代
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質の合成とそのフッ素化度の検討2011

    • Author(s)
      藤田一郎
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規人工調製肺サーファクタントの研究と高機能性特化への応用展開2011

    • Author(s)
      中原広道
    • Organizer
      第28回日本薬学会九州支部大会
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fluorocarbon-hybrid pulmonary surfactants towards thereplacement therapy: A Langmuir monolayer study2011

    • Author(s)
      中原広道
    • Organizer
      第4回コロイド及び界面化学アジア会議
    • Place of Presentation
      Tainan, Taiwan
    • Year and Date
      2011-11-25
    • Related Report
      2012 Final Research Report
  • [Presentation] Specific effects of palmitic acid in pulmonary surfactant model system2011

    • Author(s)
      柴田 攻
    • Organizer
      第4回コロイド及び界面化学アジア会議
    • Place of Presentation
      Tainan, Taiwan
    • Year and Date
      2011-11-25
    • Related Report
      2012 Final Research Report
  • [Presentation] Specific Effects of Palmitic Acid in Pulmonary Surfactant Model System2011

    • Author(s)
      Osamu Shibata
    • Organizer
      The 4th Asian Conference on Colloid and Interface Science (ACCIS)
    • Place of Presentation
      TAINAN (TAIWAN)
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fluorocarbon-Hybrid Pulmonary Surfactants towards the Replacement Therapy : A Langmuir Monolayer Study2011

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      The 4th Asian Conference on Colloid and Interface Science (ACCIS)
    • Place of Presentation
      TAINAN (TAIWAN)
    • Year and Date
      2011-11-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Examination of surface adsorption of typical cationic andanionic surfactant solutions2011

    • Author(s)
      中原広道
    • Organizer
      第4回コロイド及び界面化学アジア会議
    • Place of Presentation
      Tainan, Taiwan
    • Year and Date
      2011-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] Interaction of a partially fluorinated alcohol withdipalmitoylphosphatidylcholine atthe air-water interface2011

    • Author(s)
      中原広道
    • Organizer
      第4回コロイド及び界面化学アジア会議
    • Place of Presentation
      Tainan,Taiwan
    • Year and Date
      2011-11-24
    • Related Report
      2012 Final Research Report
  • [Presentation] Interaction of Glycyrrhizin with the Ternary Mixture of Shingomyelin/DOPC/Cholesterol by Langmuir Monolayer Study2011

    • Author(s)
      Seiichi Sakamoto
    • Organizer
      The 4th Asian Conference on Colloid and Interface Science (ACCIS)
    • Place of Presentation
      TAINAN (TAIWAN)
    • Year and Date
      2011-11-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Interaction of a Partially Fluorinated Alcohol with Dipalmitoylphosphatidylcholine at the Air-Water Interface2011

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      The 4th Asian Conference on Colloid and Interface Science (ACCIS)
    • Place of Presentation
      TAINAN (TAIWAN)
    • Year and Date
      2011-11-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Examination of Surface Adsorption of Typical Cationic and Anionic Surfactant Solutions2011

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      The 4th Asian Conference on Colloid and Interface Science (ACCIS)
    • Place of Presentation
      TAINAN (TAIWAN)
    • Year and Date
      2011-11-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 肺サーファクタントモデルにおけるパルミチン酸の役割:膜配向と排出現象2011

    • Author(s)
      中原広道
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 肺サーファクタントモデルにおけるパルミチン酸の役割:膜配向と排出現象2011

    • Author(s)
      中原広道
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] フッ素化度の異なる長鎖アルコールの合成とその基本物性2011

    • Author(s)
      藤田一郎
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 空気/溶液界面に対するSDS及びCTABの吸着様式:添加塩の効果2011

    • Author(s)
      長谷川温子
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] (Perfluorobutyl) pentadecanol (F4H11OH)とDPPCとの2成分Langmuir単分子膜挙動2011

    • Author(s)
      平野千佳代
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規長鎖部分フッ素化アルコール(FnHmOH)の合成とその物性評価2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 界面活性剤の空気/溶液界面吸着おける添加塩の効果:Langmuir 及びGibbs 膜双方の観点から2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 人工調製肺サーファクタントにおけるパルミチン酸の特異的分子挙動2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F4H11OH)と DPPC との 2 成分単分子膜挙動2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規部分フッ素化両親媒性物質(F4H11OH)とDPPCとの2成分単分子膜挙動2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都大(京都)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 人工調製肺サーファクタントにおけるパルミチン酸の特異的分子挙動2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都大(京都)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 界面活性剤の空気/溶液界面吸着おける添加塩の効果:Langmuir及びGibbs膜双方の観点から2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都大(京都)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新規長鎖部分フッ素化アルコール(FnHmOH)の合成とその物性評価2011

    • Author(s)
      中原広道
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都大(京都)
    • Year and Date
      2011-09-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effects of palmitic acid on pulmonary surfactant model systems: A Langmuir monolayer study2011

    • Author(s)
      中原広道
    • Organizer
      第25回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2011-09-05
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of added salt concentrations on surface adsorption of typical surfactants2011

    • Author(s)
      中原広道
    • Organizer
      第25回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2011-09-05
    • Related Report
      2012 Final Research Report
  • [Presentation] Surface property and miscibility of a partially fluorinated amphiphile (F4H11OH) with dipalmitoylphosphatidylcholine2011

    • Author(s)
      柴田 攻
    • Organizer
      第25回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2011-09-05
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of Added Salt Concentrations on Surface Adsorption of Typical Surfactants2011

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      25th CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      BERLIN (GERMANY)
    • Year and Date
      2011-09-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] Surface Property and Miscibility of a Partially Fluorinated Amphiphile (F4H11OH) with Dipalmitoylphosphatidylcholine2011

    • Author(s)
      Osamu Shibata
    • Organizer
      25th CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      BERLIN (GERMANY)
    • Year and Date
      2011-09-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effects of Palmitic Acid on Pulmonary Surfactant Model Systems : A Langmuir Monolayer Study2011

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      25th CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      BERLIN (GERMANY)
    • Year and Date
      2011-09-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 部分フッ素化物と生体関連脂質の二成分単分子膜挙動2011

    • Author(s)
      柴田 攻
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 部分フッ素化物を含んだ人工肺サーファクタント調製物の界面科学的評価2011

    • Author(s)
      中原広道
    • Organizer
      日本薬学会第131 年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 部分フッ素化物を含んだ人工肺サーファクタント調製物の界面科学的評価2011

    • Author(s)
      中原広道
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡県立大(静岡)
    • Year and Date
      2011-03-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 部分フッ素化物と生体関連脂質の二成分単分子膜挙動2011

    • Author(s)
      柴田攻
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡県立大(静岡)
    • Year and Date
      2011-03-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規人工調製型肺サーファクタントに関する基盤研究2011

    • Author(s)
      中原広道
    • Organizer
      第11回長崎国際大学術研究報告会
    • Place of Presentation
      長崎国際大(長崎)
    • Year and Date
      2011-02-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規人工調製肺サーファクタントに関するペプチド二次構造の解析2011

    • Author(s)
      中原広道
    • Organizer
      第4回薬学研究フォーラム in 東京~九州からの情報発信~
    • Place of Presentation
      東京
    • Year and Date
      2011-01-07
    • Related Report
      2012 Final Research Report
  • [Presentation] 新規人工調製肺サーファクタントに関するペプチド二次構造の解析2011

    • Author(s)
      中原広道
    • Organizer
      第4回薬学研究フォーラムin東京~九州からの晴報発信~
    • Place of Presentation
      東京
    • Year and Date
      2011-01-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 鎖長の異なるフッ素化アルコールの人工肺サーファクタント系への添加効果2010

    • Author(s)
      中原広道
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Year and Date
      2010-12-12
    • Related Report
      2012 Final Research Report
  • [Presentation] 部分フッ素化両親媒性物質と生体膜構成脂質の二次元相互作用2010

    • Author(s)
      柴田 攻
    • Organizer
      第27回日本薬学会九州支部大会
    • Place of Presentation
      長崎
    • Year and Date
      2010-12-12
    • Related Report
      2012 Final Research Report
  • [Presentation] 鎖長の異なるフッ素化アルコールの人工肺サーファクタント系への添加効果2010

    • Author(s)
      中原広道
    • Organizer
      第27日本薬学会九州支部大会
    • Place of Presentation
      長崎大(長崎)
    • Year and Date
      2010-12-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 部分フッ素化両親媒性物質と生体膜構成脂質の二次元相互作用2010

    • Author(s)
      柴田攻
    • Organizer
      第27日本薬学会九州支部大会
    • Place of Presentation
      長崎大(長崎)
    • Year and Date
      2010-12-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 人工肺サーファクタント系における部分フッ素化アルコールの添加効果2010

    • Author(s)
      中原広道
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2010-11-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 部分フッ素化両親媒性物質F8H11OH と生体膜構成脂質の二成分単分子膜挙動2010

    • Author(s)
      柴田 攻
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡
    • Year and Date
      2010-11-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 人工肺サーファクタント系における部分フッ素化アルコールの添加効果2010

    • Author(s)
      中原広道
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2010-11-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 部分フッ素化両親媒性物質F8H11OHと生体膜構成脂質の二成分単分子膜挙動2010

    • Author(s)
      柴田攻
    • Organizer
      物理化学インターカレッジ(兼油化学界面科学部会九州地区講演会)
    • Place of Presentation
      福岡大(福岡)
    • Year and Date
      2010-11-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mode of surfactant adsorption of soluble surfactants at the air-solution interface2010

    • Author(s)
      中原広道
    • Organizer
      ナノコロイド界面国際会議
    • Place of Presentation
      千葉
    • Year and Date
      2010-09-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Role of fluorocarbon-hybrid pulmonary surfactant preparations in the RDS treatment2010

    • Author(s)
      中原広道
    • Organizer
      ナノコロイド界面国際会議
    • Place of Presentation
      千葉
    • Year and Date
      2010-09-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Monolayer miscibility of a single-chain partially fluorinated amphiphile (F8H11OH) with biomembrane components2010

    • Author(s)
      柴田 攻
    • Organizer
      ナノコロイド界面国際会議
    • Place of Presentation
      千葉
    • Year and Date
      2010-09-21
    • Related Report
      2012 Final Research Report
  • [Presentation] Role of Fluorocarbon-Hybrid Pulmonary Surfactant Preparations in the RDS Treatment2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      INTERNATIONAL CONFERENCE ON NANOSCOPIC COLLOID AND SURFACE SCIENCE (NCSS2010)
    • Place of Presentation
      CHIBA(JAPAN)
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Langmuir Monolayer Interaction between a Single-Chain Partially Fluorinated Alcohol and Biomembrane Components2010

    • Author(s)
      Osamu Shibata
    • Organizer
      INTERNATIONAL CONFERENCE ON NANOSCOPIC COLLOID AND SURFACE SCIENCE (NCSS2010)
    • Place of Presentation
      CHIBA(JAPAN)
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mode of Surfactant Adsorption of Soluble Surfactants at the Air-Solution Interface2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      INTERNATIONAL CONFERENCE ON NANOSCOPIC COLLOID AND SURFACE SCIENCE (NCSS2010)
    • Place of Presentation
      CHIBA(JAPAN)
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 長鎖部分フッ素化アルコールを含有した人工肺サーファクタントのLangmuir 膜挙動2010

    • Author(s)
      中原広道
    • Organizer
      第49回日本油化学会年会
    • Place of Presentation
      函館
    • Year and Date
      2010-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 界面活性剤溶液の空気/溶液界面吸着に関する再検討-添加塩効果の結果から2010

    • Author(s)
      中原広道
    • Organizer
      第49回日本油化学会年会
    • Place of Presentation
      函館
    • Year and Date
      2010-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 部分フッ素化両親媒性物質と各種生体膜構成成分との二成分単分子膜挙動2010

    • Author(s)
      柴田 攻
    • Organizer
      第49回日本油化学会年会
    • Place of Presentation
      函館
    • Year and Date
      2010-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 長鎖部分フッ素化アルコールを含有した人工肺サーファクタントのLangmuir膜挙動2010

    • Author(s)
      中原広道
    • Organizer
      第49回日本油化学会年会
    • Place of Presentation
      北海道大(函館)
    • Year and Date
      2010-09-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 部分フッ素化両親媒性物質と各種生体膜構成成分との二成分単分子膜挙動2010

    • Author(s)
      柴田攻
    • Organizer
      第49回日本油化学会年会
    • Place of Presentation
      北海道大(函館)
    • Year and Date
      2010-09-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 界面活性剤溶液の空気/溶液界面吸着に関する再検討-添加塩効果の結果から2010

    • Author(s)
      中原広道
    • Organizer
      第49回日本油化学会年会
    • Place of Presentation
      北海道大(函館)
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Interfacial phenomena of surfactant adsorption induced by additive salt concentrations2010

    • Author(s)
      中原広道
    • Organizer
      第24回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2010-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Interfacial behavior of synthetic pulmonary surfactant preparations with partially fluorinated amphiphiles2010

    • Author(s)
      中原広道
    • Organizer
      第24回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2010-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Two-component miscibility of a single-chain partially fluorinated amphiphile (F8H11OH) with DPPC, DPPG,and cholesterol2010

    • Author(s)
      柴田 攻
    • Organizer
      第24回ヨーロッパ・コロイド及び界面化学会議
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2010-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Interfacial phenomena of surfactant adsorption induced by additive salt concentrations2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      24th CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      PRAGUE(CZECH REPUBLI)
    • Year and Date
      2010-09-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Interfacial behavior of synthetic pulmonary surfactant preparations with partially fluorinated amphiphiles2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      24th CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      PRAGUE(CZECH REPUBLI)
    • Year and Date
      2010-09-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Two-component miscibility of a single-chain partially fluorinated amphiphile (F8H11OH) with DPPC, DPPG, and cholesterol2010

    • Author(s)
      Osamu Shibata
    • Organizer
      24th CONFERENCE OF THE EUROPEAN COLLOID AND INTERFACE SOCIETY
    • Place of Presentation
      PRAGUE(CZECH REPUBLI)
    • Year and Date
      2010-09-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] An irreversible transformation of peptide secondary structure in pulmonary surfactantmodel systems at the air-waterinterface2010

    • Author(s)
      中原広道
    • Organizer
      第13回国際組織化膜会議
    • Place of Presentation
      Quebec, Canada
    • Year and Date
      2010-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Salt concentration effect on surfactant adsorption of soluble surfactants at the air-solution interface2010

    • Author(s)
      中原広道
    • Organizer
      第13回国際組織化膜会議
    • Place of Presentation
      Quebec, Canada
    • Year and Date
      2010-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Potential use of fluorocarbon-hybrid pulmonary surfactant preparations for the surfactant replacement therapy2010

    • Author(s)
      中原広道
    • Organizer
      第13回国際組織化膜会議
    • Place of Presentation
      Quebec,Canada
    • Year and Date
      2010-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Mode of head groups in phospholipids on miscibility with partially fluorinated amphiphiles at the air-water interface2010

    • Author(s)
      柴田攻
    • Organizer
      第13回国際組織化膜会議
    • Place of Presentation
      Quebec, Canada
    • Year and Date
      2010-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Monolayer miscibility of a single-chain partially fluorinated amphiphile (F8H11OH) with biomembrane components2010

    • Author(s)
      柴田 攻
    • Organizer
      第13回国際組織化膜会議
    • Place of Presentation
      Quebec, Canada
    • Year and Date
      2010-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] An irreversible transformation of peptide secondary structure in pulmonary surfactant model systems at the air-water interface2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      THE 13rd INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS(LB13)
    • Place of Presentation
      QUEBEC(CANADA)
    • Year and Date
      2010-06-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Salt concentration effect on surfactant adsorption of soluble surfactants at the air-solution interface2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      THE 13rd INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS(LB13)
    • Place of Presentation
      QUEBEC(CANADA)
    • Year and Date
      2010-06-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mode of Head Groups in Phospholipids on Miscibility with Partially Fluorinated Amphiphiles at the Air-Water Interface2010

    • Author(s)
      Osamu Shibata
    • Organizer
      THE 13rd INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS(LB13)
    • Place of Presentation
      QUEBEC(CANADA)
    • Year and Date
      2010-06-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Monolayer miscibility of a single-chain partially fluorinated amphiphile (F8H11OH) with biomembrane components2010

    • Author(s)
      Osamu Shibata
    • Organizer
      THE 13rd INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS(LB13)
    • Place of Presentation
      QUEBEC(CANADA)
    • Year and Date
      2010-06-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Potential use of fluorocarbon-hybrid pulmonary surfactant preparations for the surfactant replacement therapy2010

    • Author(s)
      Hiromichi Nakahara
    • Organizer
      THE 13rd INTERNATIONAL CONFERENCE ON ORGANIZED MOLECULAR FILMS(LB13)
    • Place of Presentation
      QUEBEC(CANADA)
    • Year and Date
      2010-06-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of added saltconcentrations on surface adsorption of typical surfactants2009

    • Author(s)
      中原広道
    • Organizer
      世界オレオ会議
    • Place of Presentation
      佐世保
    • Year and Date
      2009-10-02
    • Related Report
      2012 Final Research Report
  • [Presentation] Surface property of a partially fluorinated amphiphile(F8HmOH): Binary miscibility with dipalmitoylphosphatidylcholine2009

    • Author(s)
      平野千佳代
    • Organizer
      世界オレオ会議
    • Place of Presentation
      佐世保
    • Year and Date
      2009-10-02
    • Related Report
      2012 Final Research Report
  • [Presentation] Surface property and miscibility of a partially fluorinated amphiphile (F4H11OH) with dipalmitoylphosphatidylcholine2009

    • Author(s)
      柴田 攻
    • Organizer
      世界オレオ会議
    • Place of Presentation
      佐世保
    • Year and Date
      2009-10-02
    • Related Report
      2012 Final Research Report
  • [Presentation] Efficient Silkwormexpression of a fluorescent singledomain antibody against plumbaginusing Bombyx MoriNucleopolyhedrovirus Bacmid DNASystem2009

    • Author(s)
      坂元政一
    • Organizer
      世界オレオ会議
    • Place of Presentation
      佐世保
    • Year and Date
      2009-10-01
    • Related Report
      2012 Final Research Report
  • [Presentation] Interfacial phenomena ofpulmonary surfactant model systemsincorporated with fluorinatedamphiphile2009

    • Author(s)
      中原広道
    • Organizer
      世界オレオ会議
    • Place of Presentation
      佐世保
    • Year and Date
      2009-10-01
    • Related Report
      2012 Final Research Report
  • [Book] Colloids in Biotechnology;Surfactant Science Series 1522010

    • Author(s)
      柴田 攻, 中原広道, 李 相男
    • Total Pages
      521
    • Publisher
      CRC Press
    • Related Report
      2012 Final Research Report
  • [Book] Colloids in Biotechnology ; Surfactant Science Series 1522010

    • Author(s)
      Osamu Shibata, et al.
    • Total Pages
      521
    • Publisher
      CRC Press
    • Related Report
      2010 Annual Research Report
  • [Remarks] 長崎国際大学

    • URL

      http://www.niu.ac.jp/

    • Related Report
      2012 Final Research Report
  • [Remarks] 長崎国際大学薬学部薬品物理化学研究室

    • URL

      http://www.niu.ac.jp/?pharm1/lab/physchem/index.html

    • Related Report
      2012 Final Research Report
  • [Remarks] Research Gate

    • URL

      https://www.researchgate.net/home.Home.html?ref=home

    • Related Report
      2012 Final Research Report
  • [Remarks] ReaD & Researchmap

    • URL

      http://researchmap.jp/

    • Related Report
      2012 Final Research Report
  • [Remarks] 長崎国際大学

    • URL

      http://www.niu.ac.jp/

    • Related Report
      2012 Annual Research Report
  • [Remarks] 長崎国際大学薬学部 薬品物理化学研究室

    • URL

      http://www.niu.ac.jp/~pharm1/lab/physchem/index.html

    • Related Report
      2012 Annual Research Report
  • [Remarks] ResearchGate

    • URL

      https://www.researchgate.net/home.Home.html?ref=home

    • Related Report
      2012 Annual Research Report
  • [Remarks] ReaD & Researchmap

    • URL

      http://researchmap.jp/

    • Related Report
      2012 Annual Research Report
  • [Remarks] 長崎国際大学教育・研究者データペースURL

    • URL

      http://www.niu.ac.jp/

    • Related Report
      2011 Annual Research Report
  • [Remarks] 長崎国際大学薬学部薬品物理化学研究室URL

    • URL

      http://www.niu.ac.jp/~pharm1/lab/physchem/index.html

    • Related Report
      2011 Annual Research Report
  • [Remarks] ReaD & Researchmap URL

    • URL

      http://researchmap.jp/

    • Related Report
      2011 Annual Research Report
  • [Remarks] 長崎国際大学教育・研究者データベースURL

    • URL

      http://www.niu.ac.jp/

    • Related Report
      2010 Annual Research Report
  • [Remarks] 長崎国際大学薬学部薬品物理化学研究室URL

    • URL

      http://www.niu.ac.jp/~pharm1/lab/physchem/index.html

    • Related Report
      2010 Annual Research Report
  • [Remarks] 研究開発支援総合ディレクトリ(ReaD)URL

    • URL

      http://read.jst.go.jp/

    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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