| Project/Area Number |
22710120
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KIMURA Hiroshi 東京大学, 生産技術研究所, 特任助教 (40533625)
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| Research Collaborator |
FUJII Teruo 東京大学, 生産技術研究所, 教授 (30251474)
SAKAI Yasuyuki 東京大学, 生産技術研究所, 教授 (00235128)
NAKAO Yosuke 東京大学, 工学系研究科, 修士課程
IKEDA Takashi 東京大学, 工学系研究科, 修士課程
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | マイクロ流体デバイス / バイオMEMS / Body on a Chip / 細胞培養 / 薬物動態 / ADME |
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| Research Abstract |
In this project, we proposed and developed an on-chip absorption and metabolism model as an alternative method of animal tests. We performed anti-cancer drug tests with coclutured small intestine, liver and lung model cells in the device and showed a possibility of evaluation of pharmacokinetics.
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