Elucidation of functional diversity of heterochromatin using ChIP-seq
| Project/Area Number |
22710180
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Genome biology
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| Research Institution | Hokkaido University |
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Principal Investigator |
NAGAO Koji 北海道大学, 大学院・先端生命科学研究院, 助教 (60426575)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | エピゲノム / ヘテロクロマチン / バイオインフォマティクス / ゲノム |
|---|
| Research Abstract |
Heterochromatin plays an essential role for the maintenance of chromosomal integrity and the regulation of cell specific gene expression pattern. In this study, we map heterochromatin-associated proteins throughout genome using ChIP-seq(chromatin immunoprecipitation combined with high-throughput sequencing) method, and elucidate the architecture of human heterochromatin.
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Report
(3 results)
Research Products
(15 results)
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[Journal Article] CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast2011
Author(s)
Fukuura, M., Nagao, K., Obuse, C., Takahashi, T. S., Nakagawa, T., and Masukata, H.
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Journal Title
Mol. Biol. Cell
Volume: 14
Pages: 2620-2633
Related Report
Peer Reviewed
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[Journal Article] Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation2010
Author(s)
Nozawa, R. S., Nagao, K., Masuda, H. T., Iwasaki, O., Hirota, T., Nozaki, N., Kimura, H., and Obuse, C.
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Journal Title
Nat. Cell Biol
Volume: 12
Pages: 719-727
Related Report
Peer Reviewed
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