Preparation of desmosines for diagnosis of COPD by the biomarker
Project/Area Number |
22710224
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Living organism molecular science
|
Research Institution | Sophia University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | COPD / エラスチン / バイオマーカー / クロスカップリング / 全合成 / アミノ酸 |
Research Abstract |
In this study, total synthesis of desmosine and isodesmosine, knownas COPD biomarkers and elastin crosslinkers, was achieved via palladium-catalyzedcross-coupling reactions as key steps.
|
Report
(4 results)
Research Products
(81 results)
-
-
-
-
-
-
-
-
-
[Journal Article] The facilitative effects of bilobalide, a unique constituent of Ginkgo biloba, on synaptic transmission and plasticity in hippocampal subfields2011
Author(s)
Suzuki, E., Sato, M., Takezawa, R., Suzuki, E., Sato, M., Takezawa, R., Usuki, T. & Okada, T
-
Journal Title
Journal of Physiological Sciences
Volume: 61
Issue: 5
Pages: 421-427
DOI
NAID
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-