Indole/Azine C. H/C. H Coupling : Applications to Natural Products Synthesis
| Project/Area Number |
22750037
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 合成有機化学 / インドール / 天然物 / ピリジン / クロスカップリング / 炭素-水素結合官能基化 / パラジウム触媒 / dragmacidin / eudistomin U / dragmacidin D |
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| Research Abstract |
We have developed a palladium-catalyzed C-H/C-H coupling reaction of indoles or pyrroles with azine N oxides. Furthermore, we have accomplished the synthesis of marine indole alkaloid dragmacidin D and eudistomin U by utilizing this newly developed C-H/C-H coupling reaction.
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Report
(3 results)
Research Products
(31 results)
