Asymmetric Synthesis of Chiral Organosilicon Compounds and Their Applications
| Project/Area Number |
22750042
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Kyushu University |
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Principal Investigator |
IGAWA Kazunobu 九州大学, 先導物質化学研究所, 助教 (80401529)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 有機元素化学 / 不斉合成 / キラルケイ素化合物 / 有機合成 / 有機ケイ素化合物 / ケイ素不斉 / キラルカルボン酸誘導体 / シラノール |
|---|
| Research Abstract |
To efficiently approach non-racemic chiral organosilicon compounds, a novel reactive silane, which can react with nucleophiles in a stereospecific manner, and an oxidative cleavage reaction of C-Si bond with ozone have been developed. These new reactions allow to obtain a silicon congener of a-hydroxy carboxylic acid derivatives, which are difficult to obtain by other methods.
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Report
(3 results)
Research Products
(32 results)
