Development of Asymmetric Catalysis by Transition Metal Complexes with C-N Bond Axial Chirality
| Project/Area Number |
22750082
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | Chiba University |
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Principal Investigator |
MINO Takashi 千葉大学, 大学院・工学研究科, 准教授 (40302533)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 不斉配位子 / 有機化学 / 不斉合成 / 有機合成 / 合成化学 |
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| Research Abstract |
We report here the synthesis of C-N bond atropisomers of N-indole type phosphine ligandand acyclic amines. We also report their application as the chiral ligands for suchcatalytic asymmetric reactions as a palladium-catalyzed asymmetric allylic alkylationof malonate. And more, we report the palladium-catalyzed asymmetric allylic alkylationof indoles with 1,3-diphenyl-2-propenyl acetate using C-N bond axially chiral phosphineligands in good yields with moderate to high enantioselectivities.
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Report
(4 results)
Research Products
(28 results)
