Development of Environmentally Benign Selective Oxidation Reactions Using Designer Hypervalent Iodine Catalysts
| Project/Area Number |
22750087
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 選択的合成・反応 / 合成化学 / 有機化学 / 不斉合成 / 超原子価ヨウ素 / 酸化反応 / カップリング / 環境低負荷型反応 / 不斉触媒 / 機能物質科学 |
|---|
| Research Abstract |
In this study, we achieved several oxidation reactions using designer hypervalent iodine catalysts. We have developed the first example of the organoiodine(V)-catalyzed regioselective oxidation of phenols to ortho-quinones using 2-iodoxybenzenesulfonic acid (IBS). Moreover, we succeeded in the rational design of conformationally flexible iodosylarenes based on secondary nonbonding interactions as chiral catalysts for the enantioselective oxidative dearomatization of 1-naphthols. Furthermore, we have developed the intra- and intermolecular direct x-oxyacylation reactions of carbonyl compounds catalyzed by in situ-generated ammonium (hypo)iodite species with hydrogen peroxide or TBHP as an environmentally benign oxidant
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Report
(4 results)
Research Products
(97 results)
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[Book] 2-Iodobenzenesulfonic Acid2010
Author(s)
Muhammet Uyanik, Kazuaki Ishihara
Total Pages
4
Publisher
Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS), John Wiley & Sons
Related Report
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