Development of Novel Chiral Bifunctional Phase-Transfer Catalyst and Its Application to Environmentally Benign Asymmetric Reactions
| Project/Area Number |
22750093
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kyoto University |
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Principal Investigator |
SHIRAKAWA Seiji 京都大学, 大学院・理学研究科, 准教授 (60459865)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 不斉合成 / 有機触媒 / 相間移動触媒 / 環境調和型反応 / 触媒開発 / 原子効率 / 共役付加反応 / アミノ酸 / アミノ化反応 / フッ素化反応 |
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| Research Abstract |
Asymmetric phase-transfer reaction is a powerful method for the efficient synthesis of biologically active compounds. Although many examples of chiral phase-transfer catalysts have been reported, truly efficient chiral phase-transfer catalyst is still limited. In this research, we have developed novel bifunctional phase-transfer catalysts for the asymmetric synthesis of useful compounds in drug development.
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Report
(3 results)
Research Products
(30 results)
