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Fabrication of high-efficient 2-photon fluorescent materials for bio- applications using metal-particle/dye-aggregate composites

Research Project

Project/Area Number 22760012
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied materials science/Crystal engineering
Research InstitutionMeiji University

Principal Investigator

KATO Noritaka  明治大学, 理工学部, 准教授 (90329110)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords局在表面プラズモン共鳴 / 微粒子 / 色素会合体 / 非線形光学 / 光物性 / 薄膜 / 2光子励起蛍光 / J会合体 / 表面プラズモン共鳴 / 2光子励起蛍光 / J会合体
Research Abstract

The method to stabilize dye-aggregates in aqueous media was developed. The aggregates enhanced the efficiency of the 2-photon excited fluorescence by up to 100 times compared to the solubilized dyes. The method to form a gold-shell on particle was also developed. Due to the enhancement of the excitation intensity induced by the shell, the aggregates adsorbed on the shell exhibited 3 times higher efficiency than those on the particle without the shell. Thus, the combination of dye-aggregation and the gold shell achieved several 100-fold higher efficiency compared to the solubilized dyes.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (28 results)

All 2013 2012 2011 2010

All Presentation (28 results)

  • [Presentation] 近赤外領域に表面プラズモン共鳴帯をもつポリスチレン@Au型コア/シェル粒子の作製(28p-PA6-2)2013

    • Author(s)
      内藤峻之,志野木駿伍,加藤徳剛
    • Organizer
      第60回応用物理学会春季学術講演会
    • Place of Presentation
      神奈川県(神奈川工科大)
    • Year and Date
      2013-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 近赤外領域に表面プラズモン共鳴帯をもつポリスチレン@Au型コア/シェル粒子の作製2013

    • Author(s)
      加藤徳剛
    • Organizer
      第60回応用物理学会春季学術講演会
    • Place of Presentation
      神奈川県(神奈川工科大)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 飯村兼一シリカコア-金シェル型粒子上のJ会合体の2光子励起蛍光特性(13p-H2-9)2012

    • Author(s)
      内藤峻之,志野木駿伍,加藤徳剛
    • Organizer
      第73回応用物理学会学術講演会秋季
    • Place of Presentation
      愛媛県(愛媛大・松山大)
    • Year and Date
      2012-09-13
    • Related Report
      2012 Final Research Report
  • [Presentation] Two-Photon Excited Fluorescence of J-aggregates Using Surface Plasmon Resonance Excitation(2P-099)2012

    • Author(s)
      加藤徳剛,内藤峻之,宇佐美仁彦
    • Organizer
      6th International Conferenceon Gold Science,Technology and Its Applications
    • Place of Presentation
      東京都(Keio Plaza Hotel)
    • Year and Date
      2012-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Two-photon excited fluorescence properties of J-aggregate-adsorbed nanoparticles(PA-039)2012

    • Author(s)
      加藤徳剛,宇佐美仁彦,内藤峻之,飯村兼一
    • Organizer
      14th International Conferenceon Organized Molecular Films
    • Place of Presentation
      Universite Paris Descartes, France
    • Year and Date
      2012-07-11
    • Related Report
      2012 Final Research Report
  • [Presentation] J会合体と単量体の2光子励起蛍光効率の比較(18a-F9-11)2012

    • Author(s)
      仙波晴之,加藤徳剛,飯村兼一
    • Organizer
      第59回応用物理学関係連合講演会春季
    • Place of Presentation
      東京都(早大)
    • Year and Date
      2012-03-18
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 表面プラズモン共鳴励起を用いたJ会合体の2光子励起蛍光(18a-F9-10)2012

    • Author(s)
      宇佐美仁彦,加藤徳剛
    • Organizer
      第59回応用物理学関係連合講演会春季
    • Place of Presentation
      東京都(早大)
    • Year and Date
      2012-03-18
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] シリカコア-金シェル型粒子上のJ会合体の2光子励起蛍光特性2012

    • Author(s)
      加藤徳剛
    • Organizer
      秋季第73回応用物理学会学術講演会
    • Place of Presentation
      愛媛県(愛媛大・松山大)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Two-Photon Excited Fluorescence of J-aggregates Using Surface Plasmon Resonance Excitation2012

    • Author(s)
      加藤徳剛
    • Organizer
      6th International Conference on Gold Scicence, Technology and Its Applications
    • Place of Presentation
      Keio Plaza Hotel, Tokyo
    • Related Report
      2012 Annual Research Report
  • [Presentation] Two-photon excited fluorescence properties of J-aggregate-adsorbed nanoparticles2012

    • Author(s)
      加藤徳剛
    • Organizer
      14th International Conference on Organized Molecular Films
    • Place of Presentation
      Universite Paris Descartes, France
    • Related Report
      2012 Annual Research Report
  • [Presentation] Fabrication of J-aggregate-adsorbed microparticles:Toward two-photon fluorescent staining or labeling of biological samples(14PN-47)2011

    • Author(s)
      宇佐美仁彦,内藤峻之,加藤徳剛,飯村兼一
    • Organizer
      6th International Symposiumon Surface Science
    • Place of Presentation
      東京都(タワーホール船堀)
    • Year and Date
      2011-12-14
    • Related Report
      2012 Final Research Report
  • [Presentation] Fabrication of J-aggregate-adsorbed microparticles : Toward two-photon fluorescent staining or labeling of biological samples (14PN-47)2011

    • Author(s)
      宇佐美仁彦, 内藤峻之, 加藤徳剛, 飯村兼一
    • Organizer
      6th International Symposium on Surface Science
    • Place of Presentation
      東京(タワーホール船堀)
    • Year and Date
      2011-12-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] J会合体吸着微粒子の作製と2光子励起蛍光特性(3F04)2011

    • Author(s)
      加藤徳剛,宇佐美仁彦,内藤峻之,仙波晴之,飯村兼一
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都府(京大)
    • Year and Date
      2011-09-09
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 有機色素分子を複合化させた金属ナノ粒子の作製と光学特性(1E05)2011

    • Author(s)
      山本葵果,古澤毅,飯村兼一,仙波晴之,加藤徳剛
    • Organizer
      第63回コロイドおよび界面化学討論会
    • Place of Presentation
      京都府(京大)
    • Year and Date
      2011-09-07
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] J-会合体吸着微粒子の作製と二光子励起蛍光観察(30a-S-14)2011

    • Author(s)
      宇佐美仁彦,内藤峻之,加藤徳剛
    • Organizer
      第72回応用物理学会学術講演会秋季
    • Place of Presentation
      山形県(山形大)
    • Year and Date
      2011-08-30
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] J会合体分散液の2光子励起蛍光特性(30a-S-13)2011

    • Author(s)
      仙波晴之,加藤徳剛,飯村兼一
    • Organizer
      第72回応用物理学会学術講演会秋季
    • Place of Presentation
      山形県(山形大)
    • Year and Date
      2011-08-30
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] J-Aggregate-Adsorbed Nanoparticles for RGB Fluorescent Imaging Using Confocaland Two-Photon Microscopy(O28)2011

    • Author(s)
      加藤徳剛,宇佐美仁彦,仙波晴之,内藤峻之,飯村兼一
    • Organizer
      12th European Conferenceon Organized Films
    • Place of Presentation
      Sheffield,UK
    • Year and Date
      2011-07-19
    • Related Report
      2012 Final Research Report
  • [Presentation] J-Aggregate-Adsorbed Nanoparticles for RGB Fluorescent Imaging Using Confocal and Two-Photon Microscopy (O28)2011

    • Author(s)
      加藤徳剛, 宇佐美仁彦, 仙波晴之, 内藤峻之, 飯村兼一
    • Organizer
      12th European Conference on Organized Films
    • Place of Presentation
      Sheffield, UK
    • Year and Date
      2011-07-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 有機色素会合体/金属ナノ粒子複合体の構造と光学的特性(2PC-092)2011

    • Author(s)
      山本葵果,飯村兼一,古澤毅,仙波晴之,加藤徳剛
    • Organizer
      日本化学会第91春季年会(震災で講演中止)
    • Place of Presentation
      神奈川県(神奈川大横浜キャンパス)
    • Year and Date
      2011-03-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 有機色素会合体/金属ナノ粒子複合体の構造と光学的特性(2PC-092)2011

    • Author(s)
      山本葵果, 飯村兼一, 古澤毅, 仙波晴之, 加藤徳剛
    • Organizer
      日本化学会 第91春季年会
    • Place of Presentation
      神奈川県(神奈川大学横浜キャンパス)(震災で講演中止)
    • Year and Date
      2011-03-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 微粒子表面上での色素会合体の作製(25a-CD-8)2011

    • Author(s)
      宇佐美仁彦,加藤徳剛
    • Organizer
      第58回応用物理学関係連合講演会春季(震災で講演中止)
    • Place of Presentation
      神奈川県(神奈川工科大)
    • Year and Date
      2011-03-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 微粒子表面上での色素会合体の作製(25a-CD-8)2011

    • Author(s)
      宇佐美仁彦, 加藤徳剛
    • Organizer
      第58回応用物理学関係連合講演会 春季
    • Place of Presentation
      神奈川県(神奈川工科大)(震災で講演中止)
    • Year and Date
      2011-03-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fabrication of dye aggregate/metal nanoparticle complexes toward enhancement of two-photon-excited fluorescence generation(ID#1076)2010

    • Author(s)
      山本葵果,飯村兼一,加藤徳剛,仙波晴之
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu,Hawaii,USA
    • Year and Date
      2010-12-18
    • Related Report
      2012 Final Research Report
  • [Presentation] Fabrication of dye aggregate/metal nanoparticle complexes toward enhancement of two-photon-excited fluorescence generation (ID#1076)2010

    • Author(s)
      山本葵果, 飯村兼一, 加藤徳剛, 仙波晴之
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2010-12-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of metal nanoparticle-organic dye aggregate complex for enhancement of two-photon-excited fluorescence generation(1PB31)2010

    • Author(s)
      山本葵果,飯村兼一,加藤徳剛,仙波晴之
    • Organizer
      International Conferenceon Nanoscopic Colloidand Surface Science
    • Place of Presentation
      千葉県(幕張メッセ)
    • Year and Date
      2010-09-20
    • Related Report
      2012 Final Research Report
  • [Presentation] Synthesis of metal nanoparticle-organic dye aggregate complex for enhancement of two-photon-excited fluorescence generation (1PB31)2010

    • Author(s)
      山本葵果, 飯村兼一, 加藤徳剛, 仙波晴之
    • Organizer
      International Conference on Nanoscopic Colloid and Surface Science
    • Place of Presentation
      千葉県(幕張メッセ)
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] ポリイオンコンプレックスを用いた水分散型J会合体の作製(17a-K-10)2010

    • Author(s)
      仙波晴之,高田昌和,加藤徳剛,飯村兼一
    • Organizer
      第71回応用物理学会学術講演会秋季
    • Place of Presentation
      長崎県(長崎大)
    • Year and Date
      2010-09-17
    • Related Report
      2012 Final Research Report
  • [Presentation] ポリイオンコンプレックスを用いた水分散型J会合体の作製(17a-K-10)2010

    • Author(s)
      仙波晴之, 高田昌和, 加藤徳剛, 飯村兼一
    • Organizer
      第71回応用物理学会学術講演会 秋季
    • Place of Presentation
      長崎県(長崎大)
    • Year and Date
      2010-09-17
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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