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Development of thin microwave antenna inserted into endoscope for treatment of bile duct carcinoma

Research Project

Project/Area Number 22760242
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Electron device/Electronic equipment
Research InstitutionChiba University

Principal Investigator

SAITO Kazuyuki  千葉大学, フロンティアメディカル工学研究開発センター, 准教授 (80334168)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsマイクロ波・ミリ波 / がんの温熱治療 / マイクロ波微細径アンテナ / 内視鏡 / マイクロ波アンテナ / 胆管部腫瘍 / 再狭窄 / 金属ステント / 非侵襲 / 生体等価ファントム / マイクロ波治療器 / 血流による冷却効果 / 生体適合性材料
Research Abstract

The thermal treatment is one of the modalities for cancer treatment, utilizing the difference of thermal sensitivity between tumor and normal tissue. There are a few methods for heating the cancer cells inside the body. In this study, intracavitary heating is employed for treatment. In this treatment, a long flexible microwave antenna is inserted into the forceps channel of the endoscope and is led to the bile duct. In this study specifications of the microwave antenna such as diameter and length of the antenna were decided based on results of animal experiment. Moreover, the antenna structure was improved by opinion of medical doctors. In addition, heating characteristics of the antenna inserted into a metallic stent, which is frequently employed for treatment of bile duct carcinoma, could be investigated. As a result, some effective characteristics for the heating of this situation were found.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (26 results)

All 2012 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (17 results) Book (2 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] Development of microwave antennas for thermal therapy2011

    • Author(s)
      Koichi Ito, Kazuyuki Saito
    • Journal Title

      Current Pharmaceutical Design

      Volume: vol.17,no.22 Pages: 2360-2366

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Experimental evaluation of microwave antenna for thermal treatment of bile duct carcinoma2010

    • Author(s)
      Kousuke Tsubouchi, Kazuyuki Saito, Masaharu Takahashi, Koichi Ito, Toshio Tsuyuguchi, Taketo Yamaguchi, Kazuki Kato
    • Journal Title

      Thermal Medicine

      Volume: vol.26,no.4 Pages: 121-130

    • NAID

      10027646015

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Experimental evaluation of microwave antenna for thermal treatment of bile duct carcinoma2010

    • Author(s)
      Kosuke Tsubouchi, Kazuyuki Saito, Masaharu Takahashi, Koichi Ito, Toshio Tsuyuguchi, Taketo Yamaguchi, Kazuki Kato
    • Journal Title

      Thermal Medicine

      Volume: 26 Pages: 121-130

    • NAID

      10027646015

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 胆管ステントを利用したマイクロ波加温の生体等価ファントムを用いた特性評価2012

    • Author(s)
      板倉洋, 齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      第16回関東ハイパーサーミア研究会
    • Year and Date
      2012-03-24
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Microwave heating on outside of biliary stent by coaxial probe2011

    • Author(s)
      Hiroshi Itakura, Kazuyuki Saito, Masaharu Takahashi, Koichi Ito
    • Organizer
      4th International Symposium on Applied Sciences in Biomedical and Communication Technologies
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-10-26
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 留置済胆管ステントを用いたマイクロ波腔内加温法の基礎検討2011

    • Author(s)
      板倉洋, 齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      日本ハイパーサーミア学会第28回大会プログラム・抄録集
    • Year and Date
      2011-09-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 留置済胆管ステントを用いたマイクロ波腔内加温法の基礎検討2011

    • Author(s)
      板倉洋, 齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      日本ハイパーサーミア学会第28回大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2011-09-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 同軸スロットアンテナによる局所加温と腔内加温への展開2011

    • Author(s)
      齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      日本ハイパーサーミア学会第28回大会プログラム・抄録集
    • Year and Date
      2011-09-09
    • Related Report
      2011 Final Research Report
  • [Presentation] 同軸スロットアンテナによる局所加温と腔内加温への展開2011

    • Author(s)
      齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      日本ハイパーサーミア学会第28回大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2011-09-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Thin microwave antenna for intracavitary heating of bile duct carcinoma-Experimental evaluations on performances of antenna using a swine-2011

    • Author(s)
      Kazuyuki Saito, Kousuke Tsubouchi, Masaharu Takahashi, Koichi Ito
    • Organizer
      Abstract of 30th URSI General Assembly and Scientific Symposium of International Union of Radio Science
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2011-08-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Thin microwave antenna for intracavitary heating of bile duct carcinoma-Experimental evaluations on performances of antenna using a swine-2011

    • Author(s)
      Kazuyuki Saito, Kousuke Tsubouchi, Masaharu Takahashi, Koichi Ito
    • Organizer
      30th URSI General Assembly and Scientific Symposium of International Union of Radio Science
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2011-08-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 留置された胆管ステントを利用したマイクロ波加温に関する有用性の基礎検討2011

    • Author(s)
      板倉洋, 壷内晃介, 齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      第15回関東ハイパーサーミア研究会
    • Year and Date
      2011-02-26
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Animal experiment for evaluations on heating performances of microwave antenna for bile duct carcinoma2010

    • Author(s)
      Kousuke Tsubouchi, Kazuyuki Saito, Masaharu Takahashi, Koichi Ito, Toshio Tsuyuguchi
    • Organizer
      アジアハイパーサーミア腫瘍学会第5回大会・日本ハイパーサーミア学会第27回大会合同大会プログラム・抄録集
    • Year and Date
      2010-09-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Animal experiment for evaluations on heating performances of microwave antenna for bile duct carcinoma2010

    • Author(s)
      Kosuke Tsubouchi, Kazuyuki Saito, Masaharu Takahashi, Koichi Ito, Toshio Tsuyuguchi
    • Organizer
      アジアハイパーサーミア腫瘍学会第5回大会・日本ハイパーサーミア学会第27回大会合同大会
    • Place of Presentation
      福岡市
    • Year and Date
      2010-09-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胆管部腫瘍の温熱治療に用いるフレキシブルなマイクロ波アンテナの諸特性2010

    • Author(s)
      壷内晃介, 齊藤一幸, 高橋応明, 伊藤公一, 露口利夫
    • Organizer
      電子情報通信学会技術報告
    • Year and Date
      2010-09-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 内視鏡と併用する微細径マイクロ波アンテナにおける組織凝固領域の測定2010

    • Author(s)
      壷内晃介, 齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      第29回Microwave Surgery研究会, Journal of Microwave Surgery vol. 28 (増刊号)
    • Year and Date
      2010-09-03
    • Related Report
      2011 Final Research Report
  • [Presentation] 内視鏡と併用する微細径マイクロ波アンテナにおける組織凝固領域の測定2010

    • Author(s)
      壷内晃介, 齊藤一幸, 高橋応明, 伊藤公一
    • Organizer
      第29回Microwave Surgery研究会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] Practical evaluations on heating characteristics of thin microwave antenna for intracavitary thermal therapy2010

    • Author(s)
      Kazuyuki Saito, Kousuke Tsubouchi, Masaharu Takahashi, Koichi Ito
    • Organizer
      32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      Buenos Aires, Argentina
    • Year and Date
      2010-09-02
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Development of antenna for intracavitary microwave thermal therapy-Evaluations on heating characteristics of antenna using biological tissue -2010

    • Author(s)
      Kazuyuki Saito, Kousuke Tsubouchi, Masaharu Takahashi, Koichi Ito
    • Organizer
      Proceedings of 2010 IEEE AP-S International Symposium and CNC-USNC/URSI Radio Science Meeting
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2010-07-12
    • Related Report
      2011 Final Research Report
  • [Presentation] Development of antenna for intracavitary microwave thermal therapy-Evaluations on heating characteristics of antenna using biological tissue-2010

    • Author(s)
      Kazuyuki Saito, Kosuke Tsubouchi, Masaharu Takahashi, Koichi Ito
    • Organizer
      2010 IEEE AP-S International Symposium and CNC-USNC/URSI Radio Science Meeting
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2010-07-12
    • Related Report
      2010 Annual Research Report
  • [Book] エレクトロニクス機器設計と電磁波による生体影響2011

    • Author(s)
      伊藤公一, 齊藤一幸
    • Publisher
      三松(藤原修・宅間薫監修)
    • Related Report
      2011 Final Research Report
  • [Book] エレクトロニクス機器設計と電磁波による生体影響1.4節 電磁界の医療応用2011

    • Author(s)
      伊藤公一, 齊藤一幸
    • Total Pages
      200
    • Publisher
      三松
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロ波プローブ2010

    • Inventor(s)
      齊藤一幸, 伊藤公一, 露口利夫, 折田政寛
    • Industrial Property Rights Holder
      千葉大学, HOYA(株)
    • Industrial Property Number
      2010-189966
    • Filing Date
      2010-08-26
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] マイクロ波プローブ及び温熱治療装置2010

    • Inventor(s)
      齊藤一幸, 伊藤公一, 露口利夫, 折田政寛, 渡部敦
    • Industrial Property Rights Holder
      千葉大学, HOYA(株)
    • Industrial Property Number
      2010-090600
    • Filing Date
      2010-04-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロ波プローブ及び温熱治療装置2010

    • Inventor(s)
      齊藤一幸, 伊藤公一, 露口利夫, 折田政寛, 渡部敦
    • Industrial Property Rights Holder
      千葉大学, HOYA(株)
    • Industrial Property Number
      2010-090599
    • Filing Date
      2010-04-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Patent(Industrial Property Rights)] マイクロ波プローブ2010

    • Inventor(s)
      齊藤一幸,伊藤公一, 露口利夫, 折田政寛
    • Industrial Property Rights Holder
      千葉大学HOYA(株)
    • Industrial Property Number
      2010-189966
    • Filing Date
      2010-08-26
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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