Hydrothermal synthesis of ceramic films for inhibition of bone formation on titanium

• Project/Area Number: 22760546
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Structural/Functional materials
• Research Institution: Kansai University
• Principal Investigator: UEDA Masato 関西大学, 化学生命工学部, 准教授 (40362660)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 生体材料 / 表面・界面物性 / セラミックス / 表面修飾 / 骨形成制御 / 水熱処理 / 生体不活性 / ジルコニア / 生体不活 / ZrO_2

Research Abstract

TiO_2-ZrO_2 composite film could be synthesised on pure Ti by the chemical-hydrothermal combined treatment with ZrOCl_2/NH_3/C_6H_8 O_7 aqueous solution. Apatite formation and bone conduction was suppressed on the film.

Research Products

• [Journal Article] Hydrothermal Synthesis of Bioinert Oxide Film on Pure Ti : In-vitro and In-vivo Studies (2012)
  • Author(s): M. Ueda, M. Ikeda, R. Langford, J. Skepper, R. E. Cameron, S. M. Best
  • Journal Title: Proceeding of MRS Fall Meeting Volume: (in press)
  • Peer Reviewed
• [Journal Article] Chemical-Hydrothermal Synthesis of Bioinert Oxide Films on Ti Substrates (2012)
  • Author(s): M. Ueda, R. Kozakura, M. Ikeda, R. E. Cameron, S. M. Best
  • Journal Title: Proceeding of the 12th World Conference on Titanium Volume: (in press)
  • Peer Reviewed
• [Journal Article] Hydrothermal Synthesis of Bioinert TiO_2-ZrO_2 Films on Ti Substrates with Zr-dissolved Alkaline Solutions (2012)
  • Author(s): R. Kozakura, M. Ueda, M. Ikeda
  • Journal Title: Resources Processing Volume: 59 Pages: 17-21
  • Peer Reviewed
• [Journal Article] Hydrothermal synthesis of bioactive titanium oxide-CaCO_3 films with aqueous Ca(OH)_2/KHCO_3 on pure Ti (2012)
  • Author(s): Y. Suzaki, M. Ueda, M. Ikeda, K. Doi, S. Terauchi
  • Journal Title: Resources Processing Volume: 59 Pages: 22-26
  • Peer Reviewed
• [Journal Article] Chemical-Hydrothermal Synthesis of Bioinert Oxide Films on Ti Substrates (2012)
  • Author(s): M.Ueda, R.Kozakura, M.Ikeda, R.E.Cameron, S.M.Best
  • Journal Title: Proceeding of the 12th World Conference on Titanium Volume: (In press)
  • Peer Reviewed
• [Journal Article] Hydrothermal Synthesis of Bioinert Oxide Film on Pure Ti : In-vitro and In-vivo Studies (2012)
  • Author(s): M.Ueda, M.Ikeda, R.Langford, J.Skepper, R.E.Cameron, S.M.Best
  • Journal Title: Proceeding of MRS Fall Meeting Volume: (In press)
  • Peer Reviewed
• [Journal Article] Hydrothermal synthesis of bioactive titanium oxide-CaCO_3 films with aqueous Ca(OH)_2/KHCO_3 on pure Ti (2012)
  • Author(s): Y.Suzaki, M.Ueda, M.Ikeda, K.Doi, S.Terauchi
  • Journal Title: Resources Processing Volume: 59(In press)
  • Peer Reviewed
• [Journal Article] Hydrothermal Synthesis of Bioinert TiO_2-ZrO_2 Films on Ti Substrates with Zr-dissolved Alkaline Solutions (2012)
  • Author(s): R.KOZAKURA, M.UEDA, M.KEDA
  • Journal Title: Resources Processing Volume: 59(In press)
  • Peer Reviewed
• [Presentation] 化学・水熱複合処理による機能性酸化物膜の合成 (2012)
  • Author(s): 上田正人
  • Organizer: 日本金属学会2012年春期大会
  • Place of Presentation: 横浜国立大学
  • Year and Date: 2012-03-29
• [Presentation] 化学・水熱複合処理による機能性酸化物膜の合成 (2012)
  • Author(s): 上田正人
  • Organizer: 日本金属学会2012年春期大会
  • Place of Presentation: 横浜国立大学(招待講演)
  • Year and Date: 2012-03-29
• [Presentation] 化学・水熱処理によるチタンの表面修飾とその生体内外評価 (2011)
  • Author(s): 上田正人, 池田勝彦
  • Organizer: 日本金属学会機能性チタン合金研究会講演会「最新のチタン材料の表面改質の研究開発」
  • Place of Presentation: ちよだプラットフォームスクウェア(東京都)
  • Year and Date: 2011-12-16
• [Presentation] 化学・水熱処理によるチタンの表面修飾とその生体内外評価 (2011)
  • Author(s): 上田正人, 池田勝彦
  • Organizer: 日本金属学会機能性チタン合金研究会講演会「最新のチタン材料の表面改質の研究開発」
  • Place of Presentation: ちよだプラットフォームスクウェア(東京都)(招待講演)
  • Year and Date: 2011-12-16
• [Presentation] Hydrothermal Synthesis of Bioinert Oxide Film on Pure Ti : In-vitro and In-vivo Studies (2011)
  • Author(s): M. Ueda, M. Ikeda, R. Langford, J. Skepper, R. E. Cameron, S. M. Best
  • Organizer: 2011 MRS Fall Meeting & Exhibit
  • Place of Presentation: Boston, USA
  • Year and Date: 2011-11-28
• [Presentation] Hydrothermal Synthesis of Bioinert Oxide Film on Pure Ti : In-vitro and In-vivo Studies (2011)
  • Author(s): M.Ueda, M.Ikeda, R.Langford, J.Skepper, R.E.Cameron, S.M.Best
  • Organizer: 2011 MRS Fall Meeting & Exhibit
  • Place of Presentation: Boston, MA, USA
  • Year and Date: 2011-11-28
• [Presentation] Ti表面へのZrO_2含有酸化物膜の水熱合成に及ぼすクエン酸添加の影響 (2011)
  • Author(s): 小桜龍一, 上田正人, 池田勝彦
  • Organizer: 軽金属学会第121回秋期大会
  • Place of Presentation: 名古屋大学
  • Year and Date: 2011-11-12
• [Presentation] 骨形成を抑制するチタンの表面修飾,東北大学金属材料研究所共同研究ワークショップ (2011)
  • Author(s): 上田正人, 池田勝彦
  • Organizer: 日本バイオマテリアル学会東北地域講演会
  • Place of Presentation: 東北大学金属材料研究所
  • Year and Date: 2011-09-30
• [Presentation] 骨形成を抑制するチタンの表面修飾 (2011)
  • Author(s): 上田正人, 池田勝彦
  • Organizer: 東北大学金属材料研究所共同研究ワークショップ,日本バイオマテリアル学会東北地域講演会
  • Place of Presentation: 東北大学金属材料研究所(招待講演)
  • Year and Date: 2011-09-30
• [Presentation] Chemical-Hydrothermal Synthesis of Bioinert Oxide Films on Ti Substrates (2011)
  • Author(s): M. Ueda, R. Kozakura, M. Ikeda, R. E. Cameron and S. M. Best
  • Organizer: The 12th World Conference on Titanium
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-06-22
• [Presentation] Chemical-Hydrothernal Synthesis of Bioinert Oxide Films on Ti Substrates (2011)
  • Author(s): M.Ueda, R.Kozakura, M.Ikeda, R.E.Cameron, S.M.Best
  • Organizer: The 12th World Conference on Titanium
  • Place of Presentation: Beijing, China
  • Year and Date: 2011-06-22
• [Presentation] Low Temperature Synthesis of Bioactive CaTiO_3-CaCO_3 Composite Films on Ti Substrates (2011)
  • Author(s): Y. Suzaki, M. Ueda and M. Ikeda
  • Organizer: The 9th Japan/Korea International Symposium on Resources Recycling and Materials Science
  • Place of Presentation: 関西大学
  • Year and Date: 2011-05-30
• [Presentation] Low Temperature Synthesis of Bioinert ZrO_2-TiO_2 Composite Films on Ti Substrates (2011)
  • Author(s): R. Kozakura, M. Ueda, M. Ikeda
  • Organizer: The 9th Japan/Korea International Symposium on Resources Recycling and Materials Science
  • Place of Presentation: 関西大学
  • Year and Date: 2011-05-30
• [Presentation] Low Temperature Synthesis of Bioactive CaTiO_3-CaCO_3 Composite Films on Ti Substrates (2011)
  • Author(s): Y.Suzaki, M.Ueda, M.Ikeda
  • Organizer: The 9th Japan/Korea International Symposium on Resources Recycling arid Materials Science
  • Place of Presentation: 関西大学
  • Year and Date: 2011-05-30
• [Remarks]
  • URL: http://www.chemmater.kansai-u.ac.jp/ecmate/main.html
• [Remarks]
  • URL: http://www.chemmater.kansai-u.ac.jp/ecmate/main.html
• [Remarks] 化学工業日報1面(H22.8.13)「チタン合金 低温で表面改質」として本研究成果の一部が紹介された。