Regional regulation of corticosteroid in teleosts
| Project/Area Number |
22770053
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphology/Structure
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 浸透圧調節 / 鰓 / コルチゾル / コルチコイド受容体 / ステロイド代謝酵素 / 11β-HSD / ニジマス / 大西洋サケ / 11β-水酸化ステロイド脱水素酵素 / 糖質コルチコイド受容体 / 鉱質コルチコイド受容体 / アトランティックサーモン |
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| Research Abstract |
Cortisol is a major hormone and known to have multiple effects and also known to be an osomoregulatory hormone in teleosts. However, how fish tissues discriminate between these distinct corticosteroid actions is not clearly understood. The present study showed that levels of cortisol appeared to be locally regulated to the optimal levels by the action of steroidogenic enzymes.
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Report
(3 results)
Research Products
(6 results)
