| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
It is known that anterior pituitary hormone prolactin(PRL) and posterior pituitary hormone arginine vasotocin(AVT) play important roles in the expression of courtship behavior of the male newt Cynops pyrrhogaster. In this study, we demonstrated that PRL has AVT releasing activity by the organ culture technique and up-regulates the expression of AVT precursor gene. Judging from the result of reporter gene assay using vasopressin V1a receptor antagonist and the localization of AVT V1a-type receptor in the newt brain, it was concluded that the AVT V1a-type receptor is one of the most important receptor in the courtship behavior induced by AVT.
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