Genetic mechanisms of stickleback speciation

• Project/Area Number: 22770075
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Biodiversity/Systematics
• Research Institution: National Institute of Genetics (2011); Tohoku University (2010)
• Principal Investigator: KITANO Jun 国立遺伝学研究所, 新分野創造センター, 特任准教授 (80346105)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 性染色体 / 種分化 / トゲウオ / 次世代シークエンサー / 生態 / 多様性 / 魚類 / ゲノム

Research Abstract

We determined the whole genome sequence of the Japan Sea and Pacific Ocean female sticklebacks. We searched for rapidly evolving DNA-binding proteins within the hybrid male sterility QTL. By using the comparative genome hybridization, we examined the degeneration of the neo-Y chromosome and dosage compensation. We also found QTL for morphological variation between these two species. We also compiled cases of autosome-sex chromosome fusions and proposed that female meiotic drive contributes to the neo-sex chromosome evolution.

Research Products

• [Journal Article] The contribution of female meiotic drive to the evolution of neo-sex chromosomes (2012)
  • Author(s): Yoshida, K. and J. Kitano
  • Journal Title: Evolution Volume: (In press)
  • Peer Reviewed
• [Journal Article] Shifts in morphology and diet of non-native sticklebacks introduced into Japanese crater lakes (2012)
  • Author(s): Adachi, T., A. Ishikawa, S. Mori, W. Makino, M. Kume, M. Kawata, and J. Kitano
  • Journal Title: Ecology and Evolution Volume: (In press)
  • Peer Reviewed
• [Journal Article] Turnover of sex chromosomes and speciation in fishes (2012)
  • Author(s): Kitano, J. and C. L. Peichel
  • Journal Title: Environmental Biology of Fishes Volume: (In press)
  • Peer Reviewed
• [Journal Article] Reduction of sexual dimorphism in stream-resident forms of threespine stickleback(Gasterosteus aculeatus L.) (2012)
  • Author(s): Kitano, J., S. Mori, and C. L. Peichel
  • Journal Title: Journal of Fish Biology Volume: 80 Pages: 131-146
  • Peer Reviewed
• [Journal Article] The contribution of female meiotic drive to the evolution of neo-sex chromosomes (2012)
  • Author(s): Yoshida, K., J.Kitano
  • Journal Title: Evolution Volume: (in press)
  • Peer Reviewed
• [Journal Article] Shifts in morphology and diet of non-native sticklebacks introduced into Japanese crater lakes (2012)
  • Author(s): Adachi, T., A.Ishikawa, S.Mori, W.Makino, M.Kume, M.Kawata, J.Kitano
  • Journal Title: Ecology and Evolution Volume: (in press) Issue: 6 Pages: 1099-1112
  • DOI: 10.1002/ece3.235
  • Peer Reviewed
• [Journal Article] Turnover of sex chromosomes and speciation in fishes (2012)
  • Author(s): Kitano, J., C.L.Peichel
  • Journal Title: Environmental Biology of Fishes Volume: (in press) Issue: 3 Pages: 131-146
  • DOI: 10.1007/s10641-011-9853-8
  • Peer Reviewed
• [Journal Article] Divergence in sex steroid hormone signaling between sympatric species of Japanese threespine stickleback (2011)
  • Author(s): Kitano, J., Y. Kawagishi, S. Mori, C. L. Peichel, T. Makino, M. Kawata, and M. Kusakabe
  • Journal Title: PLoS ONE Volume: 6(12)
  • Peer Reviewed
• [Journal Article] Adaptive divergence in the thyroid hormone signaling pathway in the stickleback radiation (2010)
  • Author(s): Kitano, J., S. C. Lema, J. A. Luckenbach, S. Mori, Y. Kawagishi, M. Kusakabe, P. Swanson, and C. L. Peichel
  • Journal Title: Current Biology Volume: 20 Pages: 2124-2130
  • Peer Reviewed
• [Journal Article] Ecological divergence and habitat isolation between two migratory forms of Japanese threespine stickleback (Gasterosteus aculeatus) (2010)
  • Author(s): Kume, M., Kitano, J., S.Mori, T.Shibuya.
  • Journal Title: Journal of Evolutionary Biology Volume: 23 Pages: 1436-1446
  • Peer Reviewed
• [Journal Article] Adaptive divergence in the thyroid hormone signaling pathway in the stickleback radiation. (2010)
  • Author(s): Kitano, J., Lema, S.C., Luckenbach, J.A., Mori, S., Kawagishi, Y., Kusakabe, M., Swanson, P., Peichel, C.L.
  • Journal Title: Current Biology Volume: 20 Pages: 2124-2130
  • Peer Reviewed
• [Presentation] Neo-Sex Chromosome Formation and Speciation in the Japanese Sticklebacks (2012)
  • Author(s): Yoshida K, Makino T, Yamaguchi K, Shigenobu S, Hasebe M, Mori S, Peichel K, Kawata M, Toyoda A, Fujiyama A, and Kitano J
  • Organizer: Symposium : Speciation and Adaptation II
  • Place of Presentation: 岡崎
  • Year and Date: 2012-03-21
• [Presentation] Neo-Sex Chromosome Formation and Speciation in the Japanese Sticklebacks (2012)
  • Author(s): Yoshida K, Makino T, Yamaguchi K, Shigenobu S, Hasebe M, Mori S, Peichel K, Kawata M, Toyoda A, Fujiyama A, Kitano J
  • Organizer: OBC Symposium : Speciation and Adaptation II
  • Place of Presentation: 岡崎国際会議場(招待講演)
  • Year and Date: 2012-03-21
• [Presentation] Physiological genomics of speciation in sticklebacks(オーガナイザー兼) (2011)
  • Author(s): Kitano, J., Kusakabe, M.
  • Organizer: 日本動物学会
  • Place of Presentation: 旭川
  • Year and Date: 2011-09-23
• [Presentation] Physiological genomics of speciation in sticklebacks (2011)
  • Author(s): Kitano J, Kusakabe, M
  • Organizer: 日本動物学会
  • Place of Presentation: 旭川クリスタルホール
  • Year and Date: 2011-09-23
• [Presentation] エソロジトーの新展開:ゲウオをモデルに(オーガナイザー兼) (2011)
  • Author(s): 北野潤、森誠一
  • Organizer: 日本動物行動学会
  • Place of Presentation: 慶応大学
  • Year and Date: 2011-09-10
• [Presentation] エソロジーの新展開:トゲウオをモデルに (2011)
  • Author(s): 北野潤、森誠一
  • Organizer: 日本動物行動学会
  • Place of Presentation: 慶応大学
  • Year and Date: 2011-09-10
• [Presentation] Genetic basis for invasive colonization in sticklebacks (2011)
  • Author(s): Kitano, J.
  • Organizer: Symposium : Conservation genetics and genomics in fisheries at the Annual Meeting for the American Fisheries Society
  • Place of Presentation: シアトル
  • Year and Date: 2011-09-07
• [Presentation] Genetic basis for invasive colonization in sticklebacks (2011)
  • Author(s): Kitano J
  • Organizer: Annual Meeting for the American Fisheries Society
  • Place of Presentation: Washington State Convention Center
  • Year and Date: 2011-09-07
• [Presentation] Genomic and functional characterization of a neo-sex chromosome important for stickleback speciation (2011)
  • Author(s): Kitano J, Makino T, Yamaguchi K, Shigenobu S, Hasebe M, Peichel K, Mori S, and Kawata M.
  • Organizer: Symposium : Molecular bases of speciation at the Annual Meeting of the Society for Molecular Biology and Evolution
  • Place of Presentation: 京都大学
  • Year and Date: 2011-07-27
• [Presentation] Genomic and functional characterization of a neo-sex chromosome important for stickleback speciation (2011)
  • Author(s): Kitano J, Makino T, Yamaguchi K, Shigenobu S, Hasebe M, Peichel K, Mori S, Kawata M
  • Organizer: Annual Meeting of the Society for Molecular Biology and Evolution
  • Place of Presentation: 京都大学(招待講演)
  • Year and Date: 2011-07-27
• [Presentation] Genetics of Adaptation and Speciation in Sticklebacks (2010)
  • Author(s): Jun Kitano
  • Organizer: Northwest Fisheries Weekly Seminar
  • Place of Presentation: Northwest Fisheries Science Center, Seattle, WA, USA
  • Year and Date: 2010-10-07
• [Presentation] Neo-sex chromosome and speciation in sticklebacks (2010)
  • Author(s): Jun Kitano
  • Organizer: Annual Meetings of Society for the Study of Evolution
  • Place of Presentation: Oregon Convention Center, Portland, Oregon, U.S.A.
  • Year and Date: 2010-06-26
• [Presentation] Genetic mechanisms underlying stickleback speciation (2010)
  • Author(s): Jun.Kitano
  • Organizer: The BRH Seminar : Evolution & Diversity of Fishes
  • Place of Presentation: 生命誌研究館
  • Year and Date: 2010-06-24
• [Presentation] Ecological genetics in stickleback fishes : genetic mechanisms of adaptive evolution and speciation (2010)
  • Author(s): Jun Kitano
  • Organizer: 43rd Annual Meeting for the Japanese Society of Developmental Biologists Jointly Sponsored by the Asia-Pacific Developmental Biology Network
  • Place of Presentation: 京都国際会議場
  • Year and Date: 2010-06-21
• [Book] 「野外における行動進化のモデル生物としてのイトヨ」ブレインサイエンスレビュー (2012)
  • Author(s): 北野潤
  • Publisher: クバプロ出版
• [Book] 「イトヨの行動遺伝学」行動遺伝学入門 (2011)
  • Author(s): 北野潤
  • Publisher: 裳華房
• [Remarks]
  • URL: http://www.nig.ac.jp/labs/EcoGene/
• [Remarks]
  • URL: http://www.nig.ac.jp/labs/EcoGene/
• [Remarks]
  • URL: http://www.lifesci.tohoku.ac.jp/topics/topics_1011.html