| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
In previous study, we proposed that a dynamic equilibrium betweenthe multiple bound states is the molecular mechanism of the broadly selective specificity ofthe Tom20 receptor towards the divergent mitochondrial presequences. In this study, wecarried out X-ray crystal structure analysis and NMR spectroscopy experiments using newcomplexes between Tom20 and presequenses. We attempted to express of full lengthTom20 protein.
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