| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
The F gene, which controls the transport of beta-carotene from insect hemolymph into the silk gland, encoded SCRB15, a transmembrane protein which belongs to the CD36 superfamily. SCRB15 is paralogous to Cameo2, which is encoded by the C gene, which controls the transport of lutein. Elucidation of the molecular mechanisms for the difference in carotenoid specificity between SCRB15 and Cameo2 will provide mechanistic insights for the selective lipid transport by the CD36 superfamily, which is also important for the transmission of infectious pathogens
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