Molecular characterization of selective lipid transport using cocoon color genes in the silkworm
| Project/Area Number |
22770138
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional biochemistry
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
SAKUDOH Takashi 国立感染症研究所, 放射能管理室, 主任研究官 (70455393)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 膜輸送と輸送タンパク質 / 選択的脂質輸送 / カロテノイド / SR-BI / CD36 / カイコ / 繭色 |
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| Research Abstract |
The F gene, which controls the transport of beta-carotene from insect hemolymph into the silk gland, encoded SCRB15, a transmembrane protein which belongs to the CD36 superfamily. SCRB15 is paralogous to Cameo2, which is encoded by the C gene, which controls the transport of lutein. Elucidation of the molecular mechanisms for the difference in carotenoid specificity between SCRB15 and Cameo2 will provide mechanistic insights for the selective lipid transport by the CD36 superfamily, which is also important for the transmission of infectious pathogens
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] Diversity in copy number and structure of a silkworm morphogenetic gene as a result of domestication.2011
Author(s)
Sakudoh T, Nakashima T, Kuroki Y, Fujiyama A, Kohara Y, Honda N, Fujimoto H, Shimada T, Nakagaki M, Banno Y, Tsuchida K
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Journal Title
Genetics
Volume: 187(3)
Issue: 3
Pages: 965-67
DOI
Related Report
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[Journal Article] Diversity in Copy Number and Structure of a Silkworm Morphogenetic Gene as a Result of Domestication2011
Author(s)
Takashi Sakudoh, Takeharu Nakashima, Yoko Kuroki, Asao Fujiyama, Yuji Kohara, Naoko Honda, Hirofumi Fujimoto, Toru Shimada, Masao Nakagaki, Yutaka Banno, Kozo Tsuchida
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Journal Title
Genetics
Volume: VOL.187
Pages: 965-976
Related Report
Peer Reviewed
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[Presentation] クラスB スカベンジャー受容体相同遺伝子の強制発現による繭の着色2012
Author(s)
作道 隆, 飯塚 哲也, 内野 恵郎, 瀬筒 秀樹, 桑崎 誠剛, 生川 潤子, 山本 公 子, 伴野 豊, 本田 尚子, 藤本 浩文, 土田 耕三
Organizer
第80回蚕糸・昆虫機能利用学術講演会
Place of Presentation
福岡 九州大学
Year and Date
2012-03-18
Related Report
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