| Project/Area Number |
22770150
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biophysics
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 光生物 / 生体分子 / タンパク質 / 視細胞 / 錐体 / レチナール / 視物質のリン酸化 / 視物質の脱リン酸化 |
|---|
| Research Abstract |
In vertebrate retina, there are two types of visual photoreceptor cells, called rods and cones. Rods mediate night vision, and cones mediate daytime vision. It is well known cones. Rods mediate night vision, and cones mediate daytime vision. It is well known bright conditions where cones receive light stimuli continuously. In this study, we found that, in cones,(1) the efficiency of the inactivation of visual pigments by phosphorylation is strongly modulated, and(2) phosphorylated visual pigments are dephosphorylated rapidly. These mechanisms seem to enable cones to generate responses under bright conditions.
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