Functional analysis of signaling molecules regulating fate decision of epidermis and neural tissue in embryonic ectoderm
| Project/Area Number |
22770211
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
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| Research Institution | Kyoto University |
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Principal Investigator |
KUSAKABE Morioh 京都大学, 大学院・生命科学研究科, 助教 (80378843)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | シグナル伝達 / 発生・分化 / 発生 |
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| Research Abstract |
In vertebrates, embryonic ectoderm is fated to give rise to epidermis or neural tissue. We have shown that a novel one-pass transmembrane protein EIG121L promotes epidermal differentiation of Xenopus embryonic ectoderm. Our analyses also suggested that EIG121L binds to BMP receptors and has a positive role in BMP signaling during epidermal differentiation.
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Report
(3 results)
Research Products
(12 results)
