Evolution of the somatotopic map in the vertebrate hindbrain
| Project/Area Number |
22770218
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
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| Research Institution | Ehime University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 進化 / 脳・神経 / 発生・分化 / 遺伝子 / 解剖学 / 脳・神 |
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| Research Abstract |
To identify the evolutionary process of somatotopic organization in vertebrate trigeminal system, we compared trigeminal nerve organization in developing turtle, chick, and mouse. We found that, while mandibular and maxillary branch somatotopy is conserved in turtle, these branches in the chick are not strictly spatially segregated, and their position in the trigeminal tract is inversed, as compared to mouse. Furthermore, by using this specific marker in combination with Hoxa2 and axonal tracings from the periphery, we mapped the position of chick PrV in rhombomere(r) 1, unlike mouse PrV that mainly maps in r2-r3. Thus, somatotopy of trigeminal ganglion and nerve organization is only partially conserved through amniote evolution, possibly in relation to the modification of facial somatosensory structures and morphologies.
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Report
(3 results)
Research Products
(24 results)
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[Journal Article] Nervous system disruption and concomitant behavioral abnormality in early hatched pufferfish larvae exposed to heavy oil2012
Author(s)
M. Kawaguchi, Y. Sugahara, T. Watanabe, K. Irie, M. Ishida, D. Kurokawa, S. Kitamura, H. Takata, I. C. Handoh, K. Nakayama, and Y. Murakami
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Journal Title
Environ. Sci. Pollut. Res
Volume: (in press)
Related Report
Peer Reviewed
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[Journal Article] Effect of heavy oil on the development of the nervous system of floating and sinking teleost eggs2011
Author(s)
Kawaguchi, M., Irie, K., Mizuno, K., Song, J.Y., Nakayama, K., Kitamura, S., Murakami, Y.
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Journal Title
Marine Pollution Bulletin
Volume: 63
Pages: 297-302
Related Report
Peer Reviewed
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[Journal Article] Disruption of Sema3A causes abnormal neural projection in heavy oil exposed Japanese flounder larvae2011
Author(s)
Kawaguchi, M., Song, J.Y., Irie, K., Murakami, Y., Nakayama, K., Kitamura, S.
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Journal Title
Marine Pollution Bulletin
Volume: 63
Pages: 356-361
Related Report
Peer Reviewed
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