Comparative transcriptome and methylome study in humans and chimpanzees
| Project/Area Number |
22770240
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Physical anthropology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
GO Yasuhiro 京都大学, 霊長類研究所, 助教 (50377123)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 進化 / 霊長類 / ゲノム / 遺伝子発現 / チンパンジー / トランスクリプトーム / エピジェネティクス |
|---|
| Research Abstract |
Whole transcriptome analyses were performed in a human and chimpanzee trio(father. mother. child) by quantifying mRNA level in each individual. Combined polymorphic information in parents and children with the amount of allele specific gene expression in children, we can quantify allele specific gene expression in children with known parental origin. The result reveals that around 17% of genes show allele biased expression in a chimpanzee child.
|
Report
(3 results)
Research Products
(57 results)
