| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
Although it is necessary to measure melanopsin-expressing retinal ganglion cell (mRGC) responses independent of the rods and cones, conventional approaches have not allowed us to stimulate only the mRGC in the human electroretinogram (ERG). Therefore, in this study, the four-primary illumination system has been used to modulate stimulus levels to the mRGC and cones independently, the rods having been saturated by a background stimulus.
The result showed that the implicit time of the mRGC response (~80 msec) was longer than accepted values for that of rod and cone responses (~60 msec for the rods and ~30 msec for the cones). In addition, it was found that the mRGC response increased linearly with changes in light-stimulus levels, and was higher to light stimuli at low frequencies (0.5 - 10 Hz) while the response at a high frequency (30 Hz) was essentially zero.
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