| Project/Area Number |
22780035
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Plant pathology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
TAKEDA Atsushi 東京大学, 大学院・総合文化研究科, 助教 (60560779)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 植物 / 病原体相互作用 / サプレッサー / DCL1 / RNAサイレンシング / microRNA |
|---|
| Research Abstract |
RNA silencing is an anti-virus defense mechanism in plants. On the other hands, many plant viruses have RNA silencing suppressor(RSS) gene(s) to counteract RNA silencing-mediated anti-viral defense. In this study, I showed that(1) Arabidopsis DCL2, DCL4, RDR1, and RDR6 were important for the anti-viral defense through,(2) siRNA molecules moved from cell to cell and a viral RSS interfered the siRNA movement, and(3) Red clover necrotic mosaic virus(RCNMV) P27 interacted with P88 and this interaction was important for the RCNMV RSS activity.
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