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Characterization of perception mechanism of plant immune hormone using an salicylic acid agonist isolated from a chemical screening

Research Project

Project/Area Number 22780036
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Plant pathology
Research InstitutionOkayama University

Principal Investigator

NOUTOSHI Yoshiteru  岡山大学, 異分野融合先端研究コア, 助教 (70332278)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords植物 / 病害抵抗性 / ケミカルバイオロジー / 植物免疫 / 薬剤反応性
Research Abstract

Salicylic acid(SA) is a plytohormone which regulates immunity responses but its perception mechanism is still unclear. In this study, SA receptor was explored using Imprimatin C1, an SA analog. Imprimatin C1 seems to be converted to 4-chlorobenzoic acid inside plants. It mimic only SA function for downstream signaling, suggesting its function as partial agonist of SA. We isolated Imprimatin C1 insensitive Arabidopsis mutants and revealed that three of them expressed defense genes constitutively. They are expected to have mutations in SA receptor.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (12 results)

All 2012 2011 2010

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (8 results)

  • [Journal Article] A chemical biology approach reveals an opposite action between thermospermine and auxin in xylem development in Arabidopsis thaliana2012

    • Author(s)
      Yoshiomto, K., Noutoshi, Y., Hayashi, K. I., Shirasu, K., Takahashi, T. and Motose, H
    • Journal Title

      Plant and Cell Physiology

      Volume: 53(4) Pages: 635-45

    • NAID

      10030653224

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A chemical biology approach reveals an opposite action between thermospermine and auxin in xylem development in Arabidopsis thaliana2012

    • Author(s)
      K. Yoshimoto, Y. Noutoshi, K. Hayashi, K. Shirasu, T. Takahashi and H. Motose
    • Journal Title

      Plant Cell Physiol

      Volume: 53 Issue: 4 Pages: 635-645

    • DOI

      10.1093/pcp/pcs017

    • NAID

      10030653224

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] プラントアクティベーターによる植物免疫の活性化と化学遺伝学への利用2010

    • Author(s)
      鳴坂義弘, 平塚和之, 能年義輝
    • Journal Title

      化学と生物

      Volume: Vo48、No.10 Pages: 706-712

    • NAID

      10026712946

    • Related Report
      2011 Final Research Report
  • [Journal Article] プラントアクティベーターによる植物免疫の活性化と化学遺伝学への利用2010

    • Author(s)
      鳴坂義弘、平塚和之、能年義輝
    • Journal Title

      化学と生物

      Volume: 48 Pages: 706-712

    • NAID

      10026712946

    • Related Report
      2010 Annual Research Report
  • [Presentation] 多検体スクリーニングにより単離した植物免疫プライミング剤の作用機序解明2012

    • Author(s)
      能年義輝
    • Organizer
      日本植物生理学会第53回年会
    • Place of Presentation
      京都産業大学
    • Year and Date
      2012-03-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 多検体スクリーニングにより単離した植物免疫プイミング剤の作用機序解明2012

    • Author(s)
      能年義輝、岡崎正晃、横田悦子、白須賢
    • Organizer
      日本植物生理学会第53回年会
    • Place of Presentation
      京都産業大学
    • Year and Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Chemical Biology Approach toward Understanding Molecular Mechanism of Plant Immune Responses in Arabidopsis thaliana2011

    • Author(s)
      Noutoshi, Y
    • Organizer
      2011 RIKEN Chemical Biology Symposium
    • Place of Presentation
      RIKEN WAKO
    • Year and Date
      2011-10-21
    • Related Report
      2011 Final Research Report
  • [Presentation] Chemical Biology Approach toward Understanding Molecular Mechanism of Plant Immune Responses in Arabidopsis thaliana2011

    • Author(s)
      Noutoshi, Y., Okazaki, M., Yokota, E.and Shirasu, K.
    • Organizer
      2011 RIKEN Chemical Biology Symposium
    • Place of Presentation
      理化学研究所(和光)
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 薬剤探索から得た新規アゴニストを用いたサリチル酸情報伝達機構の解析2011

    • Author(s)
      能年義輝
    • Organizer
      日本植物生理学会第52回年会
    • Year and Date
      2011-03-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 薬剤探索から得た新規アゴニストを用いたサリチル酸情報伝達機構の解析2011

    • Author(s)
      能年義輝、岡崎正晃、白須賢
    • Organizer
      日本植物生理学会第52回年会
    • Place of Presentation
      (震災の為WEB発表)
    • Year and Date
      2011-03-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Chemical genetics for salicylic acid signal transduction in Arabidopsis using an analog isolated from a high-throughput screening2010

    • Author(s)
      Masateru Okazaki
    • Organizer
      EMBO Conference Series-Chemical Biology 2010
    • Place of Presentation
      EMBL Heidelberg
    • Year and Date
      2010-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] ケミカルバイオロジーによる植物免疫研究2010

    • Author(s)
      能年義輝
    • Organizer
      日本植物学会第74回大会
    • Place of Presentation
      中部大学
    • Year and Date
      2010-09-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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