Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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Research Abstract |
In B. subtilis, a undecaprenyl pyrophosphate synthase mutation was found to give rise to increased resistance to both a rare earth element scandium and bacitracin, which prevents cell wall synthesis, in addition to enhanced amylase production. Transcriptional analysis revealed no significant difference in the amylase gene expression, indicating that the effect of this mutation on amylase overproduction was exerted at the posttranscriptional level. This mutation thus has a potential to stimulate the amylase secretion.
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