| Project/Area Number |
22780088
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied biochemistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SAWANO Yoriko 東京医科歯科大学, 教養部, 准教授 (00571077)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 受容体型キナーゼ / 植物病原菌 / エリシター / X線結晶構造解析 / 核磁気共鳴解析 / 相互作用解析 / 植物 / 受容体キナーゼ / 過敏感反応 / 過敏感反応誘導 / 病原菌感染認識 / 核磁気共鳴 |
|---|
| Research Abstract |
Plants recognize molecules derived from pathogen, elicitor, and cause hypersensitive response(HR) as one of protective reaction against pathogen. Plant cysteine-rich receptor-like kinases have been reported to relate the induction of HR, and its recognition mechanim of pathogen was analyzed in this study. A candidate for elicitor, interacted with CRK, was found in yeast homogenate, and 3-D structure of CRK was solved by X-ray crystallography and the interaction site of CRK was identified by nuclear magnetic resonance spectroscopy.
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