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Studies on glycerol metabolism of hyperthermophilic arhaea

Research Project

Project/Area Number 22780091
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied biochemistry
Research InstitutionOsaka University

Principal Investigator

KOGA Yuichi  大阪大学, 大学院・工学研究科, 准教授 (30379119)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords古細菌 / 始原菌 / 超好熱菌 / グリセロール代謝 / アーキア / 古細菌(始原菌) / Glycerol代謝経路
Research Abstract

The genes related to glycerol metabolism were searched from genomic information of Thermococcus kodakarensis KOD1. From the results, the number of the genes is thought to be smaller than that of bacteria. Following analysis about those genes, e. g. enzymatic characterization, gene disruption and operon structure analysis, indicate that the glycerol metabolic pathway of T. kodakarensis is very simple to compare with that of bacteria or eukarya and have a unique regulation mechanism for the glycerol metabolism.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2012 2011 2010

All Presentation (6 results)

  • [Presentation] Structural analysis of the glycerol kinase from a hyperthermophilic archaeon Thermococcus kodakarensis KOD12012

    • Author(s)
      古賀雄一, 外尾竜太, 勝見亮太, 高野和文, 金谷茂則
    • Organizer
      日本農芸化学会年次大会
    • Year and Date
      2012-03-25
    • Related Report
      2011 Final Research Report
  • [Presentation] 超好熱古細菌(始原菌)Thermococcus kodakaraensis KOD1由来のglycerol-3-phosphate dehydrogenaseの特性解析2011

    • Author(s)
      小林淳, 古賀雄一, 高野和文, 金谷茂則
    • Organizer
      第63回日本生物工学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Structural analysis of the hexameric structure of glycerol kinase from a hyperthermophilic archaeon Thermococcus kodakarensis KOD12011

    • Author(s)
      古賀雄一, 外尾竜太, 勝見亮太, 高野和文, 金谷茂則
    • Organizer
      日本生物工学会
    • Year and Date
      2011-09-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 超好熱始原菌(古細菌)由来glycerol kinaseにおける特異な六量体構造の構造と機能2011

    • Author(s)
      古賀雄一, 外尾竜太, 勝見亮太, 高野和文, 金谷茂則
    • Organizer
      第63回日本生物工学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 超好熱古細菌(始原菌) Thermococcus kodakaraensis KOD1由来のglycerol-3-phosphate dehydrogenaseの特性解析2010

    • Author(s)
      小林淳, 古賀雄一, 高野和文, 金谷茂則
    • Organizer
      日本生物工学会
    • Year and Date
      2010-10-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 超好熱古細菌(始原菌)Thermococcus kodakaraensis KOD1由来のglycerol-3-phosphate dehydrogenaseの特性解析2010

    • Author(s)
      小林淳、古賀雄一、高野和文、金谷茂則
    • Organizer
      日本生物工学会
    • Place of Presentation
      宮崎県(宮崎市)
    • Year and Date
      2010-10-28
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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