| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
The biosynthesis of linoleic acid is generally restricted to animals capable of inserting a double bond into theω-6 position of oleic acid, and includes specific class of insects. The de novo biosynthesis of linoleic acid was demonstrated by incorporation experiments of isotope-labeled compounds in astigmatid mites. To demonstrate the direct conversion of linoleic acid into unsaturated hydrocarbon, labeled positions and incorporation rates in those compounds were determined by NMR spectra. As a result, the data support a mechanism in which linoleic acid is converted to unsaturated hydrocarbon by release of CO_2 or CO.
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