| Project/Area Number |
22780120
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Food science
|
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| Research Institution | Fukui Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | プロバイオティクス / ポリフェノール / 抗炎症作用 / 機能的相互作用 / プレバイオティクス様作用 / 腸内細菌 / 代謝 / 生理機能性 |
|---|
| Research Abstract |
Effects of probiotics, such as bifidobacteria and lactic acid bacteria, on the functions of polyphenols have been unclear. In this study, we investigated functional interactions between probiotic bacteria and polyphenols. When Bifidobacterium adolescentis and the polyphenol were co-cultured, the culture media showed the higher anti-inflammatory activity than that of the mono-culture media, suggesting that B. adolescentis may convert the polyphenol to more active compound(s). Interestingly, however, we have found that B. adolescentis may secrete anti-inflammatory compound(s), and the polyphenol may promote the secretion or the production, namely, prebiotic-like effect.
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