| Project/Area Number |
22780134
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Food science
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| Research Institution | Ishikawa Prefectural University |
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Principal Investigator |
MATSUMOTO Kenji 石川県立大学, 生物資源環境学部, 准教授 (60288701)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 生理活性 / タンニン / エネルギー代謝 / 柿タンニン / 胆汁酸吸着 / 2型糖尿病モデルマウス / 脂質代謝 / 柿 / 褐色脂肪 |
|---|
| Research Abstract |
In this study, I found that the bile acid-binding ability of young persimmon fruits was strongly correlated with the water-insoluble condensed tannin content(r=0. 909, P<0. 001). In animal experiment, kaki-tannin prevented dyslipidemia and type 2 diabetes in high fat diet-fed type 2 diabetic model mice, which was accompanied by increase of uncoupling protein-1 and-3 in the brown adipose tissue.
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