Molecular and developmental genetics of metamorphosis in fish
Project/Area Number |
22780170
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
General fisheries
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Research Institution | Tohoku University |
Principal Investigator |
YOKOI Hayato 東北大学, 大学院・農学研究科, 助教 (40569729)
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Project Period (FY) |
2010 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Keywords | 変態 / 発生 / 小型魚類 / モデル生物 |
Research Abstract |
This study aimed to accumulate the basic scientific knowledge on the metamorphosis in fish to help establishing more efficient production of the flounder aquaculture which has a huge economical impact in Japan. I conducted molecular and developmental genetic studies using medaka as a model. GFP transgenic lines were generated in order to monitor in vivo thyroid hormone level in a live fish. In another approach to establish medaka as a model system for studying metamorphosis, approximately 20 candidate marker genes that are implicated in thyroid grand development and/or thyroid hormone signaling were cloned and their embryonic expression patterns were examined.
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Report
(3 results)
Research Products
(25 results)
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[Journal Article] Evolution of developmental regulation in the vertebrate FgfD subfamily.2010
Author(s)
Jovelin, R., Yan, Y.L., He, X., Catchen, J., Amores A., Canestro, C., Yokoi H., Postlethwait, J.H.
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Journal Title
J.Exp.Zool.B : Mol.Dev.Evol.
Volume: 314B
Pages: 33-56
Related Report
Peer Reviewed
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