| Project/Area Number |
22780172
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General fisheries
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| Research Institution | Fukui Prefectural University |
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Principal Investigator |
SUETAKE Hiroaki 福井県立大学, 海洋生物資源学部, 准教授 (00334326)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 魚 / 免疫 / ケモカイン / 粘膜 |
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| Research Abstract |
In this project, two fugu mucosal chemokines were identified, One of them was expressed in the skin, gills and thymus of fugu In the skin, in situ hybridization revealed that the fugu epidermal cells expressed this chemokine. This expression pattern was consistent with the localization of the skin leukocytes. A putative receptor for this chemokine was expressed in the same organs. The second mucosal chemokine and its putative receptor were expressed in the skin, gills, thymus, and intestine of fugu. These mucosal chemokines would play pivotal roles in the fish mucosal skin immune system.
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