Physiological function of protein degradation pathway during fish development
| Project/Area Number |
22780195
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fisheries chemistry
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| Research Institution | Fisheries Research Agency |
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Principal Investigator |
IMAMURA Shintaro 独立行政法人水産総合研究センター, 中央水産研究所水産物応用開発研究センター, 主任研究員 (80510007)
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | オートファジー / ユビキチン / プロテアソーム / ゼブラフィッシュ / 胚発生 |
|---|
| Research Abstract |
The role of protein degradation pathway during fish development was characterized. Larval fish hadphysiological functions through protein degradation pathway against nutritional adaptation, migratory behavior andadaptationto environmentalstresses.Molecular chaperone CDC48 protein regulated both ubiquitin-proteasome system and autophagy, and was essential for neurodevelopment.
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Report
(4 results)
Research Products
(22 results)
