Effectof CLA on crosstalk between Myostatin and Leptin in muscle tissues on complete grass-fed beef production system
| Project/Area Number |
22780242
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 家畜生産システム / 自給飼料 / 放牧 / 赤肉生産 / 畜産学 / 組織・細胞 / 自給粗飼料 / 日本短角種 / 北里八雲牛 / 筋線維型 |
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| Research Abstract |
To further understand the complete grass-fed beef production system, we investigated the effect of CLA on crosstalk between Myostatin and Leptin in muscle tissue. We analyzed body weight, rate of muscle fiber, mRNA expression of muscle specific gene, and morphological and physiological analysis in Japanese shorthorn(N) and F2((N×salers(S))×N : NSN). We found that fast skeletal muscle fiber type switched to slow skeletal muscle fiber type, and slow skeletal muscle fiber type hypertrophied in theM. serratus ventralis. Furthermore, the concentration of serum NEFA increased during grazing period, and hypertrophy of muscle tissue was not involved with differentiation of myotube. We showed that crosstalk between Myostatin and Leptin, and theeffect of CLA on myotube formation. These finding suggested that an unknown factor in cattle serum may induce differentiation of myotube during grazing period.
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Report
(3 results)
Research Products
(23 results)
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[Journal Article] Peripheral serotonin enhances lipid metabolism by accelerating bile acid turnover.2010
Author(s)
Watanabe H., Akasaka D., Ogasawara H., Sato K., Miyake M., Saito K., Kanaya T., Takakura I., Chao G., Rose M.T., Ohwada S., Watanabe K., Yamaguchi T., Aso H.
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Journal Title
Endocrinology
Volume: 151
Pages: 4765-4775
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Peer Reviewed
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[Presentation] 放牧など自給粗飼料100%で生産した日本短角種および肉用交雑種の枝肉成績と筋線維型構成2011
Author(s)
小笠原英毅, 畔柳正, 米澤智洋, 渡邊康一, 三宅雅人, 高橋秀之, 小野泰, 大和田修一, 麻生久, 山口高弘, 寳示戸雅之
Organizer
第114回日本畜産学会大会
Place of Presentation
北里大学(青森県)
Year and Date
2011-08-27
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[Presentation] 牧場職員の研究と実践2010
Author(s)
小笠原英毅, 小野泰, 折目愛, 久保田博昭, 山田拓司, 庄司勝義, 松本英典
Organizer
平成22年度北海道・東北地域大学附属農場協議会及び農場教育研究会
Place of Presentation
山形大学(山形県)
Year and Date
2010-08-09
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[Patent(Industrial Property Rights)] 畜牛の飼養方法2012
Inventor(s)
米澤智洋,小笠原英毅,畔柳正,山田拓司,小野泰,塩谷篤史
Industrial Property Rights Holder
米澤智洋,小笠原英毅,畔柳正,山田拓司,小野泰,塩谷篤史
Filing Date
2012-01-16
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