| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
Noncytopathogenic bovine viral diarrhea virus could be classified to two biotypes, and each virus had existed together in a viral strain. One biotype could up-regulate the innate immunity of host cells, but the other suppressed it. The specific biological property of each virus was reciprocally interfered in the cells co-inoculated with the viruses, but the innate immunity of these cells was activated at various levels while being influenced from control of each virus. Co-infection of these viruses might involve in the persistent infection.
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