| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
The lifestyle-related illnesses became popular in domestic animal, especially obese, increases the risk of type 2 diabetes in cat. The CDK5 regulatory subunit-associated protein 1-like 1 (Cdkal1) gene encodes methylthiotransferase, and the gene contains risk variants for type 2 diabetes in human. Genotyping analysis of single nucleotide polymorphism (SNP) for cat Cdkal1 revealed that obese cats have different tendency from normal cats. These findings suggest that cat Cdkal1 may be a candidate marker for genetic diagnosis of obesity.
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