PET & SPECT Imaging for Canine Age-related Diseases
Project/Area Number |
22780286
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Clinical veterinary science
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Research Institution | Kitasato University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 診断 / 核医学 / イヌ / PET / SPECT / FDG / 加齢性疾患 / がん / 心臓 / QGS / PETがん診断 / FDG-PET / SUV / ハイブリッド型SPECT-CT / 心筋SPECT / 気腹 |
Research Abstract |
Because of improvement of rearing environmentin animals and development of preventive veterinary medicine, a lifetime of companion animals is prolonged andincidence ratesof age-related disease, such as a cancer and heart failure, areincreasingin clinics. For comprehending these diseases in detail, nuclear medical tomography methods, notably positron-emission-tomography(PET) and single-photon-emission-computed-tomography(SPECT), are more required now for functional imaging. However these nuclear medical tomography methods have not been established completely in veterinary medicine, PET and SPECT clinical cases in veterinary medicine had been reported in quite a few cases. This study objected established PET-cancer imaging and myocardial-SPECT methods in veterinary medicine including evaluations of image acquisition conditions, anesthesia methods, animal preparations and protection of exposure, and produced standard nuclear medicine protocols for the companion animals which was expected increasing consultation. This study completely established a fluoro-deoxy-D-glucose(FDG)-PET cancer imagingand could present normal standardized uptake values(SUV) of major organs in thorax and abdomen. Cardiac-SPECT of over 10 kg dogs was reconstructed enough for analysisin viability of cardiac muscles. In less than 10 kg dogs, pneumoperitoneum with a small amount of medical carbon dioxide could improve the spacial resolution greatly.
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Report
(3 results)
Research Products
(25 results)