Development of Highly Reactive Silyl Reagents Based on HypervalentSilicon Species, and Its Application to Catalytic Reactions
| Project/Area Number |
22790014
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kumamoto University |
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Principal Investigator |
KOTANI Shunsuke 熊本大学, 大学院先導機構, 特任助教 (50551280)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 有機化学 / 不斉合成 / 触媒反応開発 / 薬学 / 創薬科学 / 合成・プロセス化学 / 有機分子触媒 |
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| Research Abstract |
Silyl reagents can realize a several stereoselective organicreations by forming hypervalent silicon complexes with Lewis bases. In this study,trichlorosilyl triflate as a novel silyl reagent has been found to be highly reactiveand its hypervalent silicon complex with chiral phosphine oxides provided a variety ofeffective synthetic reactions.
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Report
(4 results)
Research Products
(80 results)
