Development of new synthetic reactions based on novel acid catalysts
Project/Area Number |
22790019
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Chemical pharmacy
|
Research Institution | Tokyo University of Pharmacy and Life Science |
Principal Investigator |
YANAI Hikaru 東京薬科大学, 薬学部, 助教 (10408685)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 触媒開発 / ブレンステッド酸 / ルイス酸 / 多成分反応 / 有機合成化学 / インジウム / 炭素酸 |
Research Abstract |
Synthetic organic chemistry plays an important role to develop functional chemicals. In this research, to improve the efficiency of chemical synthesis, we successfully developed highly effective acid catalyst containing C-H acid functionality. The carbon acid can be used as one of the most effective catalysts in some reactions using silicon enolates. Furthermore, we found that In(OTf)3 nicely catalyzes novel isocyanide-based multi component reactions.
|
Report
(4 results)
Research Products
(47 results)