Analysis of brain dysfunction in HFDinduced obese mice

Research Project

Project/Area Number	22790039
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Physical pharmacy
Research Institution	Kyushu University
Principal Investigator	YAMATO Mayumi 九州大学, 先端融合医療レドックスナビ研究拠点, 准教授 (30380695)
Project Period (FY)	2010 – 2011
Project Status	Completed (Fiscal Year 2011)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000) Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	生物物理化学 / 肥満症 / 脳機能 / 酸化ストレス / 代謝調節
Research Abstract	Obesity is a condition of well-developed adipose tissue, and cause functional abnormality of energy metabolism. In order to maintain the homeostasis of body weight, the brain takes the central role in transfer of energy information. Although diabetes or obesity serves as a risk-factor of the brain disease onset of Alzheimer' s disease etc, it remains unknown the mechanisms of brain injury in obesity. Therefore, we estimated brain function in high fat dietinduced obese mouse.