Regulation of microglia in endogenous neurogenesis
| Project/Area Number |
22790094
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biological pharmacy
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| Research Institution | Setsunan University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 薬理学 / ニューロン新生 / ミクログリア / 海馬 / 炎症性サイトカイン / 細胞増殖 / 一酸化窒素 / トリメチルスズ / NFκB / NOS2 |
|---|
| Research Abstract |
Our results support the possibility that pro-inflammatory cytokines released from activated microglia may be involved in promotion of endogenous neurogenesis through activation of NF-kappa B signaling pathway following the dentate neuronal loss.
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Report
(3 results)
Research Products
(23 results)
