Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Research Abstract |
To identify a novel phosphorylation signal in cell cycle progression, we searched for proteins which bound to 14-3-3 family proteins in a cell cycle-dependent manner. As a result, we found 14-3-3 participated in DNA damage checkpoint and mitotic progression through regulation of Chk1 kinase and Plk1 kinase, respectively.
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