Development of evaluation methods for comparability of mesenchymal stem cells based on glycans
Project/Area Number |
22790125
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Drug development chemistry
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Research Institution | National Institute of Health Sciences |
Principal Investigator |
HASHII Noritaka 国立医薬品食品衛生研究所, 生物薬品部, 第一室長 (20425672)
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Project Period (FY) |
2010 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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Keywords | 医薬品化学 / 再生医学 / 再生医療 / 分析化学 / 糖鎖生物学 |
Research Abstract |
For full-scale practical use of cell therapeutic products from MSCs, development of a method for distinguishing MSCs from differentiated cells is needed. We demonstrated the glycan profile alterations during early-stage of MSC differentiations. Glycan profiles can be used as a molecular index for discrimination of MSCs from differentiated cells.
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Report
(3 results)
Research Products
(11 results)
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[Journal Article] α1-3/4 fucosylation at Asn 241 ofβ-haptoglobin is a novel marker for colon cancer : A combinatorial approach for development of glycan biomarkers2012
Author(s)
S. Y. Park, S. H. Lee, N. Kawasaki, S. Itoh, K. Kang, Ryu S. Hee, N. Hashii, J. M. Kim, J. Y. Kim, Kim J. Hoe, Kim
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Journal Title
Int. J. Cancer
Volume: 130
Pages: 2366-2376
Related Report
Peer Reviewed
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[Journal Article] α1-3/4 fucosylation at Asn 241 of β-haptoglobin is a novel marker for colon cancer : A combinatorial approach for development of glycan biomarkers2012
Author(s)
Park, S.Y., Lee, S.H., Kawasaki, N., Itoh, S., Kang, K., Hee, Ryu, S., Hashii, N., Kim, J.M., Kim, J.Y., Hoe, Kim, J.
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Journal Title
Int.J.Cancer
Volume: 130
Pages: 2366-2376
Related Report
Peer Reviewed
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