Project/Area Number |
22790136
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Environmental pharmacy
|
Research Institution | Kobe Pharmaceutical University |
Principal Investigator |
MIKI Ikuya 神戸薬科大学, 薬学部, 講師 (30420467)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | ヘリコバクターハイルマニ / ウレアーゼ |
Research Abstract |
Helicobacter heilmannii infection is possibly associated with gastric MALT lymphoma in mice model and human, and however, its diagnostic method has not been established yet. In this study, we succeed in the diagnosis of its infection with gastric mucosa by analyzing pathogenic genes of H. pylori and H. heilmannii. In the next step, we tried to establish the serodiagnosis using monoclonal antibody, but our antibody showed cross-reactivity. Therefore, we are going on analyzing the other virulent genes.
|