Molecular mechanism of neuronal polarization mediated by downstream factors of SAD kinases.
Project/Area Number |
22790184
|
Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
General anatomy (including Histology/Embryology)
|
Research Institution | Niigata University |
Principal Investigator |
KISHI Masashi 新潟大学, 医歯学系, 准教授 (60573938)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | 神経細胞極性化 / 神経細胞極性 / SADキナーゼ / SAPS2 / asparaginase / 蛋白キナーゼ / 神経突起 / 軸索突起 / 樹状突起 |
Research Abstract |
The SAD kinases play central roles for neuronal polarization. During this term, we tried bioinformatic identification of proteins with consensus sequences of SAD kinase-mediated phosphorylation. We identified two downstream molecules by this method. We also identified two direct binding partners by yeast two-hybrid screen.
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Report
(3 results)
Research Products
(7 results)