• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Functional analysis of NLRR-4 gene in the mouse olfactory system during development.

Research Project

Project/Area Number 22790189
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field General anatomy (including Histology/Embryology)
Research InstitutionWakayama Medical University

Principal Investigator

BANDO Takayoshi  和歌山県立医科大学, 医学部, 学内助教 (00423963)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsNLRR-4 / 嗅覚 / 細胞接着分子 / シナプス形成 / ロイシンリッチリピート / 鋤鼻器 / フェロモン受容 / 神経発生 / NLRR4 / 神経科学 / 細胞接着因子 / 軸索誘導
Research Abstract

In this study, I investigated the expression of NLRR-4 in the olfactory system during development. I found that NLRR-4 was expressed in the olfactory epithelium, olfactory bulb, and piriform cortex. In the vomeronasal organ, NLRR-4 was detected in pheromone receptor V2R-positive-epiterial cells but not in V1R-pisitive cells. In the behavioral analysis, NLRR-4-gene knockout male mice showed reduction of the aggressive responses for the other mile mice and the avoidance behavior for male urine. These results suggested that NLRR-4 was involved in the development of the olfactory system and the function of vomeronasal system.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (2 results)

All 2011 2010

All Presentation (2 results)

  • [Presentation] 発生過程の小脳におけるNeuronal leucine-rich repeat-4の機能解析2011

    • Author(s)
      板東高功
    • Organizer
      日本神経科学学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 成獣及び発生過程におけるNeuronal leucine-rich repeat 4の発現解析2010

    • Author(s)
      板東高功
    • Organizer
      日本神経科学学会
    • Place of Presentation
      神戸コンベンショナルセンター
    • Year and Date
      2010-09-02
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi