Architecture of top-down signals conveyed toward extrastriate cortex revealed by rabies virus in the macaque monkey.
Project/Area Number |
22790202
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
General physiology
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Research Institution | The University of Tokyo |
Principal Investigator |
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Project Period (FY) |
2010 – 2012
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Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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Keywords | 大脳視覚野 / 狂犬病ウイルス / マカクサル |
Research Abstract |
We investigated the architecture of multi-synaptic top-down pathways toward visual area4 (V4) of ventral stream and visual area 5 (MT/V5) of dorsal stream, employing retrograde trans-synaptic transport of rabies virus. In addition, multi-synaptic architecture from the medial temporal lobe to V4 was also investigated. We found that frontal inputs to MT/V5 and V4 mainly arise from area 46v. In addition, we found shot-cut pathway from the hippocampus proper to V4. These results indicate that multi-synaptic architecture may provide top-down information about object recognition accomplished throughoccipito-temporal and occipito-parietal pathways.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] Default mode of brain function in monkeys2011
Author(s)
Mantini D, Gerits A, Nelissen K, Durand JB, Joly O, Simone L, Sawamura H, Wardak C, Orban GA, Buckner RL, Vanduffel W
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Journal Title
Journal of Neuroscience
Volume: 31
Issue: 36
Pages: 12954-12962
DOI
Related Report
Peer Reviewed
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