Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Research Abstract |
D-dopachrome tautomerase whose mRNA levels are decreased in obese adipocytes acts to regulate contents of triacylglycerol in adipocytes. In this study, DDT was found to regulate expression and activity of molecules involved in lipid metabolism in adipocytes. Furthermore, administration of DDT improved the glucose intolerance in obese mice. These results suggested that DDT acts as an adipokine with anti-obese property.
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