| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
Transcription factor-induced reprogramming requires relative longer time compared to those by nuclear transfer and cell fusion. Since cells actively proliferate during this period, we can imagine its importance in reprogramming process. However, the role of cell proliferation was unclear. In this study, we demonstrated that cell proliferation is dispensable for the initiation of reprogramming but essential for the maturation.
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